Vše

Co hledáte?

Vše
Projekty
Výsledky výzkumu
Subjekty

Rychlé hledání

  • Projekty podpořené TA ČR
  • Významné projekty
  • Projekty s nejvyšší státní podporou
  • Aktuálně běžící projekty

Chytré vyhledávání

  • Takto najdu konkrétní +slovo
  • Takto z výsledků -slovo zcela vynechám
  • “Takto můžu najít celou frázi”

Seroprevalence of Tick-borne encephalitis in dogs in the Czech Republic in 2017

Identifikátory výsledku

  • Kód výsledku v IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F18%3A43876387" target="_blank" >RIV/62157124:16170/18:43876387 - isvavai.cz</a>

  • Výsledek na webu

  • DOI - Digital Object Identifier

Alternativní jazyky

  • Jazyk výsledku

    angličtina

  • Název v původním jazyce

    Seroprevalence of Tick-borne encephalitis in dogs in the Czech Republic in 2017

  • Popis výsledku v původním jazyce

    Tick-borne encephalitis (TBE) is a tick-transmitted infection that can affect both humans and dogs. Czech Republic is one of the most affected countries in Europe. Every year hundreds of people are diagnosed and only dozens of dogs are diagnosed. Increased human and dog mobility and global climate changes have led to an increased spread and contact between the vectors and hosts. In the dog there is only limited information about TBE seroprevalence and clinical manifestations. The aim of this study was to detect seroprevalence of antibodies against TBE in the Czech Republic in 2017 and find clinical signs of infection in dogs. A total of 65 different dogs, patients at the Small Animal Clinic, University of Veterinary and Pharmaceutical Sciences Brno were tested during the year 2017. The sera were separated and stored until examination at -80°C. The assay was performed serologically using a commercial ELISA kit (IMMUNOZYM FSME IgG all-species kit, Progen Biotechnik GmbH) which allows to evaluate the concentration of specific antibodies against the TBE virus of the isotype IgG in VIEU/ml units. Ranges of sample results in VIEU/ml were: less than 63 - negative, 63-26 - borderline, more than 126 - positive. Samples of sera were examined with following results: 78.46% (51 dogs) negative, 13.85% (9 dogs) borderline and 15.6% (5 dogs) positive. In 5 dogs, the cerebrospinal fluid (CSF) was also examined. Three serologically negative dogs had a negative CSF score, 1 dubious and 1 positive had a positive antibody result in CSF. Clinical diagnoses in borderline dogs were (every disease having 1 individual): chronic renal failure (CRF), intestinal foreign body, peritonitis, arrhythmia (with positive Borrelia serology), meningoencephalitis (ME), vestibular syndrome, and 3 clinically healthy dogs. Clinical signs of serologically positive dogs: one with CRF and pancreatopathy, other one mammary gland tumor, one had metastatic tumor, another ME, and one meningomyeloradikuloneuritis (Bannwarth syndrome). Dogs are more resistant to show clinical signs than human beings. This study confirms that dogs can be infected and can show clinical signs.

  • Název v anglickém jazyce

    Seroprevalence of Tick-borne encephalitis in dogs in the Czech Republic in 2017

  • Popis výsledku anglicky

    Tick-borne encephalitis (TBE) is a tick-transmitted infection that can affect both humans and dogs. Czech Republic is one of the most affected countries in Europe. Every year hundreds of people are diagnosed and only dozens of dogs are diagnosed. Increased human and dog mobility and global climate changes have led to an increased spread and contact between the vectors and hosts. In the dog there is only limited information about TBE seroprevalence and clinical manifestations. The aim of this study was to detect seroprevalence of antibodies against TBE in the Czech Republic in 2017 and find clinical signs of infection in dogs. A total of 65 different dogs, patients at the Small Animal Clinic, University of Veterinary and Pharmaceutical Sciences Brno were tested during the year 2017. The sera were separated and stored until examination at -80°C. The assay was performed serologically using a commercial ELISA kit (IMMUNOZYM FSME IgG all-species kit, Progen Biotechnik GmbH) which allows to evaluate the concentration of specific antibodies against the TBE virus of the isotype IgG in VIEU/ml units. Ranges of sample results in VIEU/ml were: less than 63 - negative, 63-26 - borderline, more than 126 - positive. Samples of sera were examined with following results: 78.46% (51 dogs) negative, 13.85% (9 dogs) borderline and 15.6% (5 dogs) positive. In 5 dogs, the cerebrospinal fluid (CSF) was also examined. Three serologically negative dogs had a negative CSF score, 1 dubious and 1 positive had a positive antibody result in CSF. Clinical diagnoses in borderline dogs were (every disease having 1 individual): chronic renal failure (CRF), intestinal foreign body, peritonitis, arrhythmia (with positive Borrelia serology), meningoencephalitis (ME), vestibular syndrome, and 3 clinically healthy dogs. Clinical signs of serologically positive dogs: one with CRF and pancreatopathy, other one mammary gland tumor, one had metastatic tumor, another ME, and one meningomyeloradikuloneuritis (Bannwarth syndrome). Dogs are more resistant to show clinical signs than human beings. This study confirms that dogs can be infected and can show clinical signs.

Klasifikace

  • Druh

    O - Ostatní výsledky

  • CEP obor

  • OECD FORD obor

    30502 - Other medical science

Návaznosti výsledku

  • Projekt

  • Návaznosti

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Ostatní

  • Rok uplatnění

    2018

  • Kód důvěrnosti údajů

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů