Intravenous alfaxalone anaesthesia in leopard geckos (Eublepharis macularius).

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F18%3A43876937" target="_blank" >RIV/62157124:16170/18:43876937 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1053/j.jepm.2017.08.008" target="_blank" >http://dx.doi.org/10.1053/j.jepm.2017.08.008</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1053/j.jepm.2017.08.008" target="_blank" >10.1053/j.jepm.2017.08.008</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Intravenous alfaxalone anaesthesia in leopard geckos (Eublepharis macularius).

Popis výsledku v původním jazyce

Intravenous alfaxalone, administered at a dose of 5mg/kg in the jugular vein, was evaluated in 20 leopard geckos (Eublepharis macularius) to ascertain its ability to provide a level of anaesthesia. The induction time, time to loss of mandibular tone, interval of deep anaesthesia, and full recovery time were27.5 ? 30.7 seconds(10 to 56seconds),1.3 ? 1.4 minutes (11seconds to 4minutes),12.5 ? 2.2 minutes(11.11 to 15.39 minutes), and18.8 ? 12.1 minutes (10.4 to 52.31minutes), respectively. A significant reduction in heart rate (74 ? 12.9 beats/minute) between 2 and 24 minutes after alfaxalone administration was recorded. A significant decrease of respiratory rate (26.8 ? 10.1 breaths/minute) was recorded 2 minutes after alfaxalone administration and respiratory rate remained lower than basal respiratory (31.4 ? 3.1 breaths/minute) for 24minutes,but without statistical significance. The intravenous administration of alfaxalone in leopard geckos achieved a rapid onset of anasthesia and a suitable recovery time. Based on this investigation the afaxalone dose and administration site has proved to be a suitable protocol for sedation before tracheal intubation through maintenance on gas anaesthesia. Moreover, the administration technique, jugular administration of the drug, was acceptable in leopard geckos, in which other venipuncture sites are challenging or inaccessible.

Název v anglickém jazyce

Intravenous alfaxalone anaesthesia in leopard geckos (Eublepharis macularius).

Popis výsledku anglicky

Intravenous alfaxalone, administered at a dose of 5mg/kg in the jugular vein, was evaluated in 20 leopard geckos (Eublepharis macularius) to ascertain its ability to provide a level of anaesthesia. The induction time, time to loss of mandibular tone, interval of deep anaesthesia, and full recovery time were27.5 ? 30.7 seconds(10 to 56seconds),1.3 ? 1.4 minutes (11seconds to 4minutes),12.5 ? 2.2 minutes(11.11 to 15.39 minutes), and18.8 ? 12.1 minutes (10.4 to 52.31minutes), respectively. A significant reduction in heart rate (74 ? 12.9 beats/minute) between 2 and 24 minutes after alfaxalone administration was recorded. A significant decrease of respiratory rate (26.8 ? 10.1 breaths/minute) was recorded 2 minutes after alfaxalone administration and respiratory rate remained lower than basal respiratory (31.4 ? 3.1 breaths/minute) for 24minutes,but without statistical significance. The intravenous administration of alfaxalone in leopard geckos achieved a rapid onset of anasthesia and a suitable recovery time. Based on this investigation the afaxalone dose and administration site has proved to be a suitable protocol for sedation before tracheal intubation through maintenance on gas anaesthesia. Moreover, the administration technique, jugular administration of the drug, was acceptable in leopard geckos, in which other venipuncture sites are challenging or inaccessible.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40301 - Veterinary science

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Exotic Pet Medicine

ISSN

1557-5063

e-ISSN

—

Svazek periodika

27

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

4

Strana od-do

11-14

Kód UT WoS článku

000440126200003

EID výsledku v databázi Scopus

2-s2.0-85047609953