Comparison of Intracytoplasmic Sperm Injection and Preselected Intracytoplasmic Sperm Injection by Time-Lapse Monitoring

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F19%3A43878262" target="_blank" >RIV/62157124:16170/19:43878262 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.reproductivemedicine.com/toc/auto_abstract.php?id=24761" target="_blank" >http://www.reproductivemedicine.com/toc/auto_abstract.php?id=24761</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Comparison of Intracytoplasmic Sperm Injection and Preselected Intracytoplasmic Sperm Injection by Time-Lapse Monitoring

Popis výsledku v původním jazyce

OBJECTIVE: To compare the methods of fertilization using intracytoplasmic sperm injection (ICSI) and preselected intracytoplasmic sperm injection (PICSI) via the assessment of time parameters during an early development of embryos by the timelapse monitoring system. STUDY DESIGN: In total, 258 embryos destined for embryo transfer by 136 couples undergoing in vitro fertilization (IVF) cycle with donated oocytes were evaluated retrospectively. The first patient group underwent the PICSI fertilization method and the second group the ICSI method. Exact time parameters of early embryo development were compared. RESULTS: The chance of clinical pregnancy is slightly decreased with the increasing time when the embryo has reached the 8-cell stage (p=0.017). Clinical pregnancy rate for the PICSI method was 54.9% and 50% for the ICSI method (odds ratio=1.216, 95% CI 0.611-2.42, p=0.065). By using the PICSI method there was a 22% greater chance of clinical pregnancy. This increase is not statistically significant. CONCLUSION: Our findings noted an important contribution of the PICSI method. We will continue to monitor the development of the pregnancy arising from this study, in order to contribute to a clarification whether the sperm bound to hyaluronic acid increases the chance of maintaining a pregnancy and carrying the fetus to term.

Název v anglickém jazyce

Comparison of Intracytoplasmic Sperm Injection and Preselected Intracytoplasmic Sperm Injection by Time-Lapse Monitoring

Popis výsledku anglicky

OBJECTIVE: To compare the methods of fertilization using intracytoplasmic sperm injection (ICSI) and preselected intracytoplasmic sperm injection (PICSI) via the assessment of time parameters during an early development of embryos by the timelapse monitoring system. STUDY DESIGN: In total, 258 embryos destined for embryo transfer by 136 couples undergoing in vitro fertilization (IVF) cycle with donated oocytes were evaluated retrospectively. The first patient group underwent the PICSI fertilization method and the second group the ICSI method. Exact time parameters of early embryo development were compared. RESULTS: The chance of clinical pregnancy is slightly decreased with the increasing time when the embryo has reached the 8-cell stage (p=0.017). Clinical pregnancy rate for the PICSI method was 54.9% and 50% for the ICSI method (odds ratio=1.216, 95% CI 0.611-2.42, p=0.065). By using the PICSI method there was a 22% greater chance of clinical pregnancy. This increase is not statistically significant. CONCLUSION: Our findings noted an important contribution of the PICSI method. We will continue to monitor the development of the pregnancy arising from this study, in order to contribute to a clarification whether the sperm bound to hyaluronic acid increases the chance of maintaining a pregnancy and carrying the fetus to term.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Reproductive Medicine

ISSN

0024-7758

e-ISSN

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Svazek periodika

64

Číslo periodika v rámci svazku

3-4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

125-130

Kód UT WoS článku

000462002600009

EID výsledku v databázi Scopus

2-s2.0-85078266466