Glutathione redox state, glutathione peroxidase activity and selenium concentration in periparturient dairy cows, and their relation with negative energy balance

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F20%3A43878986" target="_blank" >RIV/62157124:16170/20:43878986 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.jafs.com.pl/Glutathione-redox-state-glutathione-peroxidase-activity-and-selenium-concentration,117867,0,2.html" target="_blank" >http://www.jafs.com.pl/Glutathione-redox-state-glutathione-peroxidase-activity-and-selenium-concentration,117867,0,2.html</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.22358/jafs/117867/2020" target="_blank" >10.22358/jafs/117867/2020</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Glutathione redox state, glutathione peroxidase activity and selenium concentration in periparturient dairy cows, and their relation with negative energy balance

Popis výsledku v původním jazyce

The aim of the study was to evaluate glutathione redox state, glutathione peroxidase (GPx) activity, and selenium (Se), non-esterified fatty acids (NEFA) and beta-hydroxybutyrate (BHB) concentrations in 15 Holstein periparturient dairy cows and to monitor the effect of negative energy balance (NEB) on the level of oxidative processes ongoing in dairy cows in postpartum period. The body condition score (BCS) was recorded and blood samples were collected 4 times during periparturient period. A significantly increased NEFA concentration was recorded on calving day (P &lt; 0.05) and 7 days postpartum (p.p.; P &lt; 0.01) compared to 7 days ante partum (a.p.). The reduced glutathione (GSH) concentration was significantly decreased on calving day and 7 days p.p. (P &lt; 0.05) as compared to 7 days a.p. The oxidized glutathione (GSSG) concentration was significantly higher 7 days p.p. as compared to calving day (P &lt; 0.01) and 14 days p.p. (P &lt; 0.05). Between the GSSG concentration and the GSH/GSSG ratio was found a significantly negative (r = -0.84; P &lt; 0.001) correlation. The significant decrease in GPx activity was found 14 days p.p. as compared to 7 days a.p. (P &lt; 0.05). The BCS value was significantly positively correlated (r = 0.44; P&lt; 0.05) with GSSG concentration. The results of the study indicate significant changes of antioxidant/oxidant markers and also confirm that in the postpartum period oxidative stress occurs in dairy cows. It also seems that BCS correlates with these indicators and may influence the level of oxidative processes in cows during the periparturient period.

Název v anglickém jazyce

Glutathione redox state, glutathione peroxidase activity and selenium concentration in periparturient dairy cows, and their relation with negative energy balance

Popis výsledku anglicky

The aim of the study was to evaluate glutathione redox state, glutathione peroxidase (GPx) activity, and selenium (Se), non-esterified fatty acids (NEFA) and beta-hydroxybutyrate (BHB) concentrations in 15 Holstein periparturient dairy cows and to monitor the effect of negative energy balance (NEB) on the level of oxidative processes ongoing in dairy cows in postpartum period. The body condition score (BCS) was recorded and blood samples were collected 4 times during periparturient period. A significantly increased NEFA concentration was recorded on calving day (P &lt; 0.05) and 7 days postpartum (p.p.; P &lt; 0.01) compared to 7 days ante partum (a.p.). The reduced glutathione (GSH) concentration was significantly decreased on calving day and 7 days p.p. (P &lt; 0.05) as compared to 7 days a.p. The oxidized glutathione (GSSG) concentration was significantly higher 7 days p.p. as compared to calving day (P &lt; 0.01) and 14 days p.p. (P &lt; 0.05). Between the GSSG concentration and the GSH/GSSG ratio was found a significantly negative (r = -0.84; P &lt; 0.001) correlation. The significant decrease in GPx activity was found 14 days p.p. as compared to 7 days a.p. (P &lt; 0.05). The BCS value was significantly positively correlated (r = 0.44; P&lt; 0.05) with GSSG concentration. The results of the study indicate significant changes of antioxidant/oxidant markers and also confirm that in the postpartum period oxidative stress occurs in dairy cows. It also seems that BCS correlates with these indicators and may influence the level of oxidative processes in cows during the periparturient period.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40301 - Veterinary science

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Animal and Feed Sciences

ISSN

1230-1388

e-ISSN

—

Svazek periodika

29

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

PL - Polská republika

Počet stran výsledku

8

Strana od-do

19-26

Kód UT WoS článku

000524176900003

EID výsledku v databázi Scopus

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