Plasma bile acids in healthy green iguanas and iguanas with chronic liver diseases

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F23%3A43880583" target="_blank" >RIV/62157124:16170/23:43880583 - isvavai.cz</a>

Výsledek na webu

<a href="https://vetmed.agriculturejournals.cz/pdfs/vet/2023/09/03.pdf" target="_blank" >https://vetmed.agriculturejournals.cz/pdfs/vet/2023/09/03.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.17221/10/2023-VETMED" target="_blank" >10.17221/10/2023-VETMED</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Plasma bile acids in healthy green iguanas and iguanas with chronic liver diseases

Popis výsledku v původním jazyce

The aim of the study was to establish reference values for plasma bile acid (BA) concentrations in a collection of healthy green iguanas and to compare the results with BA concentrations in iguana patients presented to the clinic with various types of chronic liver diseases, patients with other chronic diseases and healthy iguanas that were presented for routine or pre-surgical health check-up. The concentration of BA was determined using the enzymatic colorimetric method. Mean plasma bile acid concentration in 110 samples from healthy green iguanas fasted for 24 h was higher (15.89 +/- 15.61 mu mol/l) than plasma bile acid concentration in the same iguanas fasted for 48 h (9.56 +/- 8.52 mu mol/l) (P &lt; 0.01). The 3 alpha-hydroxy bile acid concentration was significantly altered in 9 patients suffering from chronic liver diseases (diagnosed by histology) (84.85 +/- 22.29 &lt;mu&gt;mol/l). BA concentration in one iguana with hepatocellular adenoma (13.0 mu mol/l) was within the interval of BA in healthy iguanas. Mean plasma BA concentration in 10 green iguanas that were suffering from various types of chronic diseases, but without any hepatopathy was 7.85 +/- 4.86 mu mol/l. The mean plasma BA concentration in 18 samples from green iguanas presented to the clinic for routine health check-ups and 17 green iguana females with preovulatory follicle stasis (POFS) syndrome presented for ovariectomy was 11.95 +/- 9.43 mu mol/l and 12.97 +/- 9.06 mu mol/l, respectively. The data collected from this study suggest that plasma bile acids are significantly increased in green iguanas suffering from chronic liver diseases.

Název v anglickém jazyce

Plasma bile acids in healthy green iguanas and iguanas with chronic liver diseases

Popis výsledku anglicky

The aim of the study was to establish reference values for plasma bile acid (BA) concentrations in a collection of healthy green iguanas and to compare the results with BA concentrations in iguana patients presented to the clinic with various types of chronic liver diseases, patients with other chronic diseases and healthy iguanas that were presented for routine or pre-surgical health check-up. The concentration of BA was determined using the enzymatic colorimetric method. Mean plasma bile acid concentration in 110 samples from healthy green iguanas fasted for 24 h was higher (15.89 +/- 15.61 mu mol/l) than plasma bile acid concentration in the same iguanas fasted for 48 h (9.56 +/- 8.52 mu mol/l) (P &lt; 0.01). The 3 alpha-hydroxy bile acid concentration was significantly altered in 9 patients suffering from chronic liver diseases (diagnosed by histology) (84.85 +/- 22.29 &lt;mu&gt;mol/l). BA concentration in one iguana with hepatocellular adenoma (13.0 mu mol/l) was within the interval of BA in healthy iguanas. Mean plasma BA concentration in 10 green iguanas that were suffering from various types of chronic diseases, but without any hepatopathy was 7.85 +/- 4.86 mu mol/l. The mean plasma BA concentration in 18 samples from green iguanas presented to the clinic for routine health check-ups and 17 green iguana females with preovulatory follicle stasis (POFS) syndrome presented for ovariectomy was 11.95 +/- 9.43 mu mol/l and 12.97 +/- 9.06 mu mol/l, respectively. The data collected from this study suggest that plasma bile acids are significantly increased in green iguanas suffering from chronic liver diseases.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40301 - Veterinary science

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Veterinární medicína

ISSN

0375-8427

e-ISSN

1805-9392

Svazek periodika

68

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

368-374

Kód UT WoS článku

001104620200002

EID výsledku v databázi Scopus

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