Hodnocení xenoestrogenního potenciálu propylparabenu u dania pruhovaného (D. rerio).

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F06%3A00000966" target="_blank" >RIV/62157124:16270/06:00000966 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Brominated flame retardants in the environment: their sources and effects (review).

Popis výsledku v původním jazyce

Brominated flame retardants (BFRs) are organic substances frequently used in many industries. The most important group within BFRs are polybrominated diphenyl ethers (PBDEs). Because they persist in the environment, get accumulated in food chains and have toxic effects, they are a potential health risk for both animals and man. Polybrominated diphenyl ethers may disrupt processes of hormonal regulation in living organisms by reducing thyroxine concentrations in the plasma of exposed individuals. In vitro studies have demonstrated the ability of these substances to bind to estrogen and androgen receptors. Tests on rodents have also demonstrated neurotoxicity of some of the PBDEs. Although industrial use of PBDEs is now regulated to a large extent, PBDEshave already been detected in areas with no apparent industrial load, e.g. in Greenland. This article presents an overview of BFRs-related issues with a particular emphasis on PBDEs, describes toxic effects of those substances and their

Název v anglickém jazyce

Brominated flame retardants in the environment: their sources and effects (review).

Popis výsledku anglicky

Brominated flame retardants (BFRs) are organic substances frequently used in many industries. The most important group within BFRs are polybrominated diphenyl ethers (PBDEs). Because they persist in the environment, get accumulated in food chains and have toxic effects, they are a potential health risk for both animals and man. Polybrominated diphenyl ethers may disrupt processes of hormonal regulation in living organisms by reducing thyroxine concentrations in the plasma of exposed individuals. In vitro studies have demonstrated the ability of these substances to bind to estrogen and androgen receptors. Tests on rodents have also demonstrated neurotoxicity of some of the PBDEs. Although industrial use of PBDEs is now regulated to a large extent, PBDEshave already been detected in areas with no apparent industrial load, e.g. in Greenland. This article presents an overview of BFRs-related issues with a particular emphasis on PBDEs, describes toxic effects of those substances and their

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Neuroendocrinology Letters

ISSN

0172-780X

e-ISSN

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Svazek periodika

27

Číslo periodika v rámci svazku

N

Stát vydavatele periodika

SE - Švédské království

Počet stran výsledku

4

Strana od-do

104-107

Kód UT WoS článku

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EID výsledku v databázi Scopus

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