Studium vlivu quercetinu na biochemické ukazatele u potkanů

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F06%3A00000997" target="_blank" >RIV/62157124:16270/06:00000997 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Study of influence quercetin on biochemical parameters at sewer rats

Popis výsledku v původním jazyce

Flavonoids are a group of polyphenolic compounds widely distributed throughout the plant kingdom. More than 4,000 flavonoids discovered to date can be classified into several classes. Flavonoids have received considerable attention because of their beneficial effects as antioxidants in the prevention of human diseases such as cancer, and some pathological disorder. Several mechanisms by which flavonoids play an important role in cytotoxicity have been identified. Anti-tumour activity of several flavonoids (e.g. quercetin) is attributed to their efficiencies to inhibit topoisomerase I and II. On the other hand, certain flavonoids like some other xenobiotics can induce activity of cytochrome P450s, which are responsible for activation of several carcinogens. Quercetin (3,5,7,3´,4´ - pentahydroxyflavon) belongs to mostly abundant flavonoids. Facts mentioned above and increasing content of flavonoids in the environment demonstrate the necessity of taking into account study of their influen

Název v anglickém jazyce

Study of influence quercetin on biochemical parameters at sewer rats

Popis výsledku anglicky

Flavonoids are a group of polyphenolic compounds widely distributed throughout the plant kingdom. More than 4,000 flavonoids discovered to date can be classified into several classes. Flavonoids have received considerable attention because of their beneficial effects as antioxidants in the prevention of human diseases such as cancer, and some pathological disorder. Several mechanisms by which flavonoids play an important role in cytotoxicity have been identified. Anti-tumour activity of several flavonoids (e.g. quercetin) is attributed to their efficiencies to inhibit topoisomerase I and II. On the other hand, certain flavonoids like some other xenobiotics can induce activity of cytochrome P450s, which are responsible for activation of several carcinogens. Quercetin (3,5,7,3´,4´ - pentahydroxyflavon) belongs to mostly abundant flavonoids. Facts mentioned above and increasing content of flavonoids in the environment demonstrate the necessity of taking into account study of their influen

Druh

M - Uspořádání konference

CEP obor

CG - Elektrochemie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Místo konání akce

Brno

Stát konání akce

CZ - Česká republika

Datum zahájení akce

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Datum ukončení akce

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Celkový počet účastníků

260

Počet zahraničních účastníků

170

Typ akce podle státní přísl. účastníků

WRD - Celosvětová akce