Protein carbonyls and traditional biomarkers in pigs exposed to low-dose gamma-radiation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F13%3A43871983" target="_blank" >RIV/62157124:16270/13:43871983 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.rvsc.2012.09.002" target="_blank" >http://dx.doi.org/10.1016/j.rvsc.2012.09.002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.rvsc.2012.09.002" target="_blank" >10.1016/j.rvsc.2012.09.002</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Protein carbonyls and traditional biomarkers in pigs exposed to low-dose gamma-radiation

Popis výsledku v původním jazyce

Response of pigs to irradiation manifested by production of protein carbonyls and adaptable enzymes was studied in two experiments. In one experiment, 10 mixed-sex pigs were exposed to 0.5 Gy whole body 60Co irradiation. In the other experiment, anotherbatch of 10 pigs was exposed to 1.0 Gy half-body irradiation. Unlike those exposed to half-body irradiation, the pigs exposed to whole-body irradiation showed significant increase in protein carbonyls by 73%, and a decrease in cholesterol by 25.7%, compared to the control group. In both cases of dose-dependent irradiation exposure, pigs showed a decrease in alanine aminotransferase activity compared with the control group. At the dose of 1 Gy, ALT activity decreased significantly by 27.7%. Aspartate aminotransferase activity in pigs after half-body irradiation decreased significantly by 65.5%. Although low doses of ionizing radiation were applied, monitoring of the above biochemical parameters helped define the pigs' biological response

Název v anglickém jazyce

Protein carbonyls and traditional biomarkers in pigs exposed to low-dose gamma-radiation

Popis výsledku anglicky

Response of pigs to irradiation manifested by production of protein carbonyls and adaptable enzymes was studied in two experiments. In one experiment, 10 mixed-sex pigs were exposed to 0.5 Gy whole body 60Co irradiation. In the other experiment, anotherbatch of 10 pigs was exposed to 1.0 Gy half-body irradiation. Unlike those exposed to half-body irradiation, the pigs exposed to whole-body irradiation showed significant increase in protein carbonyls by 73%, and a decrease in cholesterol by 25.7%, compared to the control group. In both cases of dose-dependent irradiation exposure, pigs showed a decrease in alanine aminotransferase activity compared with the control group. At the dose of 1 Gy, ALT activity decreased significantly by 27.7%. Aspartate aminotransferase activity in pigs after half-body irradiation decreased significantly by 65.5%. Although low doses of ionizing radiation were applied, monitoring of the above biochemical parameters helped define the pigs' biological response

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CE - Biochemie

OECD FORD obor

—

Projekt

—

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Research in Veterinary Science

ISSN

0034-5288

e-ISSN

—

Svazek periodika

94

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

5

Strana od-do

214-218

Kód UT WoS článku

000316039300005

EID výsledku v databázi Scopus

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