Effect of prochloraz fungicide on neopterin and biopterin concentrations in blood plasma of common carp
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F14%3A43872948" target="_blank" >RIV/62157124:16270/14:43872948 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.2754/avb201483020101" target="_blank" >http://dx.doi.org/10.2754/avb201483020101</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2754/avb201483020101" target="_blank" >10.2754/avb201483020101</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Effect of prochloraz fungicide on neopterin and biopterin concentrations in blood plasma of common carp
Popis výsledku v původním jazyce
Neopterin and biopterin are often used as markers of cell mediated immunity. The aim of this study was to evaluate the effect of prochloraz on neopterin and biopterin concentrations in blood plasma of common carp as possible indicators for monitoring perturbations of the immune system caused by xenobiotics like pesticides. Prochloraz is a widely used imidazole fungicide in horticulture and agriculture. A total of 60 juvenile common carp were divided into four groups of 15 fish and exposed to prochlorazat concentrations of 0, 50, 150 and 380 mu g.l(-1), respectively. The total length of exposure was 28 days. Neopterin and biopterin concentrations were determined by reverse phase high performance liquid chromatography with fluorescence detection. Our results indicated that concentrations of neopterin (25 +/- 7.6 nmol.l(-1)) and biopterin (190 29 nmol.l(-1)) in plasma of untreated common carp were comparable with those in mammals. Neopterin concentrations significantly (P { 0.01) increas
Název v anglickém jazyce
Effect of prochloraz fungicide on neopterin and biopterin concentrations in blood plasma of common carp
Popis výsledku anglicky
Neopterin and biopterin are often used as markers of cell mediated immunity. The aim of this study was to evaluate the effect of prochloraz on neopterin and biopterin concentrations in blood plasma of common carp as possible indicators for monitoring perturbations of the immune system caused by xenobiotics like pesticides. Prochloraz is a widely used imidazole fungicide in horticulture and agriculture. A total of 60 juvenile common carp were divided into four groups of 15 fish and exposed to prochlorazat concentrations of 0, 50, 150 and 380 mu g.l(-1), respectively. The total length of exposure was 28 days. Neopterin and biopterin concentrations were determined by reverse phase high performance liquid chromatography with fluorescence detection. Our results indicated that concentrations of neopterin (25 +/- 7.6 nmol.l(-1)) and biopterin (190 29 nmol.l(-1)) in plasma of untreated common carp were comparable with those in mammals. Neopterin concentrations significantly (P { 0.01) increas
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
GJ - Choroby a škůdci zvířat, veterinární medicina
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
Z - Vyzkumny zamer (s odkazem do CEZ)
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Acta veterinaria Brno
ISSN
0001-7213
e-ISSN
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Svazek periodika
83
Číslo periodika v rámci svazku
2
Stát vydavatele periodika
CZ - Česká republika
Počet stran výsledku
5
Strana od-do
101-105
Kód UT WoS článku
000339086600006
EID výsledku v databázi Scopus
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