The effect of antidepressants in surface water on Danio rerio organism

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F18%3A43876970" target="_blank" >RIV/62157124:16270/18:43876970 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00027162:_____/19:N0000156

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The effect of antidepressants in surface water on Danio rerio organism

Popis výsledku v původním jazyce

The concentration of antidepressants occurring in surface water is rising worldwide because of their ineffective removal at wastewater treatment plants. However, the knowledge of their impact on aquatic organisms is limited. For our assay, three different antidepressants with different mechanisms of action were chosen to assess the impact on the Danio rerio body formation mechanism. The antidepressants were tested in two concentrations ? environmentally-relevant (according to literature sources) and 100x higher. The method used was relative gene expression and genes were selected as representatives of the heart, brain, spine, eye and mesoderm formation. The results showed that the gene expression mechanism and welfare status are disrupted already in environmentally-relevant concentrations.

Název v anglickém jazyce

The effect of antidepressants in surface water on Danio rerio organism

Popis výsledku anglicky

The concentration of antidepressants occurring in surface water is rising worldwide because of their ineffective removal at wastewater treatment plants. However, the knowledge of their impact on aquatic organisms is limited. For our assay, three different antidepressants with different mechanisms of action were chosen to assess the impact on the Danio rerio body formation mechanism. The antidepressants were tested in two concentrations ? environmentally-relevant (according to literature sources) and 100x higher. The method used was relative gene expression and genes were selected as representatives of the heart, brain, spine, eye and mesoderm formation. The results showed that the gene expression mechanism and welfare status are disrupted already in environmentally-relevant concentrations.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

40301 - Veterinary science

Projekt

<a href="/cs/project/LO1218" target="_blank" >LO1218: Zdravé zvíře jako zdroj zdravé potraviny</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

MendelNet 2018 - Proceedings of 25th International PhD Students Conference

ISBN

978-80-7509-597-8

ISSN

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e-ISSN

neuvedeno

Počet stran výsledku

5

Strana od-do

160-164

Název nakladatele

Mendelova univerzita v Brně

Místo vydání

Brno

Místo konání akce

Brno

Datum konání akce

7. 11. 2018

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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