Macrophage-inhibitory cytokine-1 (MIC-1) in differential diagnosis of dyspnea - a pilot study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F09%3A00002101" target="_blank" >RIV/62157124:16370/09:00002101 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Macrophage-inhibitory cytokine-1 (MIC-1) in differential diagnosis of dyspnea - a pilot study

Popis výsledku v původním jazyce

Background: Macrophage inhibitory cytokine-1 (MIC-1) has recently been associated with markers of heart function. Aim: This study sought to verify the relationship between markers of heart function (New York Heart Association classification (NYHA)): leftventricle ejection fraction (LVEF), N terminal prohormone of natriuretic peptide B type (NT-proBNP) and MIC-1. Furthermore, the assessment of the usefulness of these markers for differential diagnosis of the myocardial form of dyspnea was explored. Methods: 124 patients (65 women and 59 men) were examined for dyspnea without signs of acute coronary syndrome. All patients underwent echocardiography (calculation of left ventricle ejection fraction-LVEF), and serum NT-proBNP and MIC-1 were determined. 21healthy individuals were defined as the control group. Results and discussion: Patients were divided into two groups: A-individuals with non-cardiogenic form of dyspnea, n = 77 and B-individuals with cardiogenic ethiology of dyspnea, n =

Název v anglickém jazyce

Macrophage-inhibitory cytokine-1 (MIC-1) in differential diagnosis of dyspnea - a pilot study

Popis výsledku anglicky

Background: Macrophage inhibitory cytokine-1 (MIC-1) has recently been associated with markers of heart function. Aim: This study sought to verify the relationship between markers of heart function (New York Heart Association classification (NYHA)): leftventricle ejection fraction (LVEF), N terminal prohormone of natriuretic peptide B type (NT-proBNP) and MIC-1. Furthermore, the assessment of the usefulness of these markers for differential diagnosis of the myocardial form of dyspnea was explored. Methods: 124 patients (65 women and 59 men) were examined for dyspnea without signs of acute coronary syndrome. All patients underwent echocardiography (calculation of left ventricle ejection fraction-LVEF), and serum NT-proBNP and MIC-1 were determined. 21healthy individuals were defined as the control group. Results and discussion: Patients were divided into two groups: A-individuals with non-cardiogenic form of dyspnea, n = 77 and B-individuals with cardiogenic ethiology of dyspnea, n =

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2009

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Clinical Biochemistry

ISSN

0009-9120

e-ISSN

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Svazek periodika

42

Číslo periodika v rámci svazku

13-14

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

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Kód UT WoS článku

000272261800002

EID výsledku v databázi Scopus

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