Phenolic Metabolites of Karwinskia humboldtiana Leaves

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Phenolic Metabolites of Karwinskia humboldtiana Leaves

Popis výsledku v původním jazyce

Phenolic Metabolites of Karwinskia humboldtiana Leaves Methanolic extract from leaves of Karwinskia humboldtiana (Schuh.) Zucc. was subjected to fractionation with a pair of immiscible solvents and subsequently tested for antioxidant activity. Using DPPHthe order of scavenging activities of the extracts in comparison with standards of L-ascorbic acid and quercetin was as follows: ethyl acetate fraction } L-ascorbic acid } quercetin } butan-1-ol } light petrol } chloroform } water. The capability of scavenging OH radicals determined by EPR was as follows: ethyl acetate, chloroform } light petrol } butan-1-ol } water fractions. On the basis of availability and antioxidant activity of these fractions, isolation of constituents from butanol fractions wasachieved. Separation of this fraction led to the isolation of (+)-epicatechin and flavonol derivatives quercetin, quercetin 3-O-glucoside (isoquercitrin), quercetin-3-O-galactoside (hyperosid), quercetin-3-O-arabinoside, quercetin 3-O-rut

Název v anglickém jazyce

Phenolic Metabolites of Karwinskia humboldtiana Leaves

Popis výsledku anglicky

Phenolic Metabolites of Karwinskia humboldtiana Leaves Methanolic extract from leaves of Karwinskia humboldtiana (Schuh.) Zucc. was subjected to fractionation with a pair of immiscible solvents and subsequently tested for antioxidant activity. Using DPPHthe order of scavenging activities of the extracts in comparison with standards of L-ascorbic acid and quercetin was as follows: ethyl acetate fraction } L-ascorbic acid } quercetin } butan-1-ol } light petrol } chloroform } water. The capability of scavenging OH radicals determined by EPR was as follows: ethyl acetate, chloroform } light petrol } butan-1-ol } water fractions. On the basis of availability and antioxidant activity of these fractions, isolation of constituents from butanol fractions wasachieved. Separation of this fraction led to the isolation of (+)-epicatechin and flavonol derivatives quercetin, quercetin 3-O-glucoside (isoquercitrin), quercetin-3-O-galactoside (hyperosid), quercetin-3-O-arabinoside, quercetin 3-O-rut

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Chemické listy

ISSN

0009-2770

e-ISSN

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Svazek periodika

106

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

4

Strana od-do

1143-1146

Kód UT WoS článku

000313406500010

EID výsledku v databázi Scopus

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