DEOXYNIVALENOL, A TRICHOTHECENE MYCOTOXIN: REVIEW OF ITS MASKED FORM, CONTAMINATION IN CEREAL-BASED FEED, AND MASS SPECTROMETRY ANALYTICAL METHODS

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18450%2F15%3A50003754" target="_blank" >RIV/62690094:18450/15:50003754 - isvavai.cz</a>

Výsledek na webu

<a href="http://mmsl.cz/viCMS/soubory/pdf/MMSL_2015_3_2_WWW.pdf" target="_blank" >http://mmsl.cz/viCMS/soubory/pdf/MMSL_2015_3_2_WWW.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

DEOXYNIVALENOL, A TRICHOTHECENE MYCOTOXIN: REVIEW OF ITS MASKED FORM, CONTAMINATION IN CEREAL-BASED FEED, AND MASS SPECTROMETRY ANALYTICAL METHODS

Popis výsledku v původním jazyce

Deoxynivalenol (DON) is a trichothecene mycotoxin regularly occurring in cereals. It is toxic to humans and inhibits DNA, RNA and protein synthesis. Moreover, its conjugated products, called masked mycotoxins, including DON-3-glucoside (DON-3G), is another "emerging" food safety issue in recent years. In this review, we first discussed the nature of contamination of masked DON in cereal-based food and feed; moreover, the new reported masked DON is summarized and we also focused on its toxicity and digestion in human and animal bodies. In addition, the contamination of DON in cereal-based feed in different countries was summarized and some regular patterns of DON occurrence are suggested. Finally, the LC-MS methods for the determination of DON and masked DON in food, feed and animal fluids were compared. This review will provide further information for DON and masked DON contamination and shed some light on the mycotoxin control strategies.

Název v anglickém jazyce

DEOXYNIVALENOL, A TRICHOTHECENE MYCOTOXIN: REVIEW OF ITS MASKED FORM, CONTAMINATION IN CEREAL-BASED FEED, AND MASS SPECTROMETRY ANALYTICAL METHODS

Popis výsledku anglicky

Deoxynivalenol (DON) is a trichothecene mycotoxin regularly occurring in cereals. It is toxic to humans and inhibits DNA, RNA and protein synthesis. Moreover, its conjugated products, called masked mycotoxins, including DON-3-glucoside (DON-3G), is another "emerging" food safety issue in recent years. In this review, we first discussed the nature of contamination of masked DON in cereal-based food and feed; moreover, the new reported masked DON is summarized and we also focused on its toxicity and digestion in human and animal bodies. In addition, the contamination of DON in cereal-based feed in different countries was summarized and some regular patterns of DON occurrence are suggested. Finally, the LC-MS methods for the determination of DON and masked DON in food, feed and animal fluids were compared. This review will provide further information for DON and masked DON contamination and shed some light on the mycotoxin control strategies.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Vojenské zdravotnické listy=Military medical science letters

ISSN

0372-7025

e-ISSN

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Svazek periodika

84

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

11

Strana od-do

104-114

Kód UT WoS článku

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EID výsledku v databázi Scopus

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