A Global View on Narcolepsy – a Review Study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18450%2F18%3A50005173" target="_blank" >RIV/62690094:18450/18:50005173 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62690094:18470/18:50005173 RIV/00179906:_____/18:10373127 RIV/61988987:17110/18:A20020QB

Výsledek na webu

<a href="http://dx.doi.org/10.2174/1389557516666160801095630" target="_blank" >http://dx.doi.org/10.2174/1389557516666160801095630</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2174/1389557516666160801095630" target="_blank" >10.2174/1389557516666160801095630</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A Global View on Narcolepsy – a Review Study

Popis výsledku v původním jazyce

Narcolepsy is an incurable neurological disorder when the brain is not able to regulate a sleep and wakefulness cycle correctly. The affected person suddenly falls asleep during the day or he/she suffers from excessive day sleepiness. In addition, people may also suffer from cataplexy, hypnagogic hallucinations, sleep paralysis, and disturbed nighttime sleep. Objective: The purpose of this review study is to provide the latest information on both clinical and socioeconomic issues in the field of narcolepsy treatment and emphasize its benefits and limitations. Methods: The methodological approaches include a method of literature review of available sources exploring the issue of narcolepsy, both from a global and specific perspective point of view. On the basis of evaluation of these literature sources, the researched issue is examined. Results: The main benefits (e.g., new drugs are being testes or non-invasive cognitive behavioral therapies are being applied) and limitations (e.g., late diagnosis of the disease or lifelong and costly treatment) of the treatment of narcolepsy are highlighted. Conclusion: The findings call for more research in the field of the development of novel drugs reflecting understanding of the neurological basis of narcolepsy and early diagnosis in order to eliminate the symptoms of narcolepsy and prevent the development of this disease.

Název v anglickém jazyce

A Global View on Narcolepsy – a Review Study

Popis výsledku anglicky

Narcolepsy is an incurable neurological disorder when the brain is not able to regulate a sleep and wakefulness cycle correctly. The affected person suddenly falls asleep during the day or he/she suffers from excessive day sleepiness. In addition, people may also suffer from cataplexy, hypnagogic hallucinations, sleep paralysis, and disturbed nighttime sleep. Objective: The purpose of this review study is to provide the latest information on both clinical and socioeconomic issues in the field of narcolepsy treatment and emphasize its benefits and limitations. Methods: The methodological approaches include a method of literature review of available sources exploring the issue of narcolepsy, both from a global and specific perspective point of view. On the basis of evaluation of these literature sources, the researched issue is examined. Results: The main benefits (e.g., new drugs are being testes or non-invasive cognitive behavioral therapies are being applied) and limitations (e.g., late diagnosis of the disease or lifelong and costly treatment) of the treatment of narcolepsy are highlighted. Conclusion: The findings call for more research in the field of the development of novel drugs reflecting understanding of the neurological basis of narcolepsy and early diagnosis in order to eliminate the symptoms of narcolepsy and prevent the development of this disease.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

30104 - Pharmacology and pharmacy

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Mini-reviews in medicinal chemistry

ISSN

1389-5575

e-ISSN

—

Svazek periodika

18

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

AE - Spojené arabské emiráty

Počet stran výsledku

7

Strana od-do

458-464

Kód UT WoS článku

000425108700006

EID výsledku v databázi Scopus

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