Jatropha gossypiifolia L. and its biologically active metabolites: A mini review

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F19%3A50015505" target="_blank" >RIV/62690094:18470/19:50015505 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60076658:12110/19:43899107 RIV/00179906:_____/19:10393183

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/abs/pii/S0378874118319780" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0378874118319780</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jep.2019.01.022" target="_blank" >10.1016/j.jep.2019.01.022</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Jatropha gossypiifolia L. and its biologically active metabolites: A mini review

Popis výsledku v původním jazyce

Ethnopharmacological relevance: Jatropha gossypiifolia L. (Euphorbiaceae) is popularly known as bellyache bush or black physic nut and is widely used in local / traditional medicine due to the various biological activities attributed to its different parts, including its leaves, roots, and latex. Aim of the study: In this review, we aim to update and discuss the chemistry, specific pharmacology, and toxicological activities of Jatropha gossypiifolia and its bioactive metabolites. Materials and methods: The Web of Science, PubMed, Google Scholar, SciFinder, Cochrane Library, Scopus, and Science Direct databases were searched with the name &quot;Jatropha gossypiifolia&quot; and the term &quot;bioactive metabolites&quot;. All studies on the chemistry, pharmacology, and toxicology of the plant up to December 2018 were included in this review. Results: Jatropha gossypiifolia leaves are considered to have anti-inflammatory, antimicrobial and insecticidal properties. The root and stem have anti-inflammatory and antimicrobial properties. The seeds and fruits can be used against influenza and as a sedative, analgesic or anti-diarrheal agents. The latex is bactericidal and molluscicidal. Topical application of latex is used to treat wounds and bites of venomous animals. The diluted form is usually used for the treatment of diarrhoea by indigenous peoples. Conclusions: The main pharmacological activities of Jatropha gossypiifolia include anti-inflammatory, antineoplastic, antimicrobial, antioxidant, and anticholinesterase, and antihypertensive activities. Species of Jatropha are notably known for their toxic potential, and their toxicity is primarily related to the latex and seed contents. However, the potential mechanisms of these pharmacological activities have not been fully explored. We hope this review will help to further inform the potential utilization of Jatropha gossypiifolia in complementary and alternative medicine.

Název v anglickém jazyce

Jatropha gossypiifolia L. and its biologically active metabolites: A mini review

Popis výsledku anglicky

Ethnopharmacological relevance: Jatropha gossypiifolia L. (Euphorbiaceae) is popularly known as bellyache bush or black physic nut and is widely used in local / traditional medicine due to the various biological activities attributed to its different parts, including its leaves, roots, and latex. Aim of the study: In this review, we aim to update and discuss the chemistry, specific pharmacology, and toxicological activities of Jatropha gossypiifolia and its bioactive metabolites. Materials and methods: The Web of Science, PubMed, Google Scholar, SciFinder, Cochrane Library, Scopus, and Science Direct databases were searched with the name &quot;Jatropha gossypiifolia&quot; and the term &quot;bioactive metabolites&quot;. All studies on the chemistry, pharmacology, and toxicology of the plant up to December 2018 were included in this review. Results: Jatropha gossypiifolia leaves are considered to have anti-inflammatory, antimicrobial and insecticidal properties. The root and stem have anti-inflammatory and antimicrobial properties. The seeds and fruits can be used against influenza and as a sedative, analgesic or anti-diarrheal agents. The latex is bactericidal and molluscicidal. Topical application of latex is used to treat wounds and bites of venomous animals. The diluted form is usually used for the treatment of diarrhoea by indigenous peoples. Conclusions: The main pharmacological activities of Jatropha gossypiifolia include anti-inflammatory, antineoplastic, antimicrobial, antioxidant, and anticholinesterase, and antihypertensive activities. Species of Jatropha are notably known for their toxic potential, and their toxicity is primarily related to the latex and seed contents. However, the potential mechanisms of these pharmacological activities have not been fully explored. We hope this review will help to further inform the potential utilization of Jatropha gossypiifolia in complementary and alternative medicine.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30104 - Pharmacology and pharmacy

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF ETHNOPHARMACOLOGY

ISSN

0378-8741

e-ISSN

—

Svazek periodika

234

Číslo periodika v rámci svazku

April

Stát vydavatele periodika

IE - Irsko

Počet stran výsledku

7

Strana od-do

197-203

Kód UT WoS článku

000461404300019

EID výsledku v databázi Scopus

2-s2.0-85061375873