Diverse roles of long non-coding RNAs in viral diseases
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F21%3A50017376" target="_blank" >RIV/62690094:18470/21:50017376 - isvavai.cz</a>
Výsledek na webu
<a href="https://onlinelibrary.wiley.com/doi/10.1002/rmv.2198" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/rmv.2198</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/rmv.2198" target="_blank" >10.1002/rmv.2198</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Diverse roles of long non-coding RNAs in viral diseases
Popis výsledku v původním jazyce
Viral infection leads to large alterations in the host transcriptome and stimulates an antiviral host immune response involving numerous proteins and signalling pathways. Long non-coding RNAs (lncRNAs) have emerged as important regulators during viral infection. Emerging data demonstrates that lncRNAs play essential roles at the host pathogen interface modulating viral infection by either antiviral response at distinct level including pathogen recognition receptors or by epigenetic, transcriptional, and post-transcriptional effects. Furthermore, differentially expressed lncRNAs may be employed as prognostic and diagnostic biomarkers for viral diseases. Here, we summarize the current knowledge of lncRNAs and their functions in viral infections with a specific focus on host-virus responses. In addition, the potential implications of lncRNAs in severe acute respiratory syndrome coronavirus 2 will be discussed. © 2020 John Wiley & Sons Ltd.
Název v anglickém jazyce
Diverse roles of long non-coding RNAs in viral diseases
Popis výsledku anglicky
Viral infection leads to large alterations in the host transcriptome and stimulates an antiviral host immune response involving numerous proteins and signalling pathways. Long non-coding RNAs (lncRNAs) have emerged as important regulators during viral infection. Emerging data demonstrates that lncRNAs play essential roles at the host pathogen interface modulating viral infection by either antiviral response at distinct level including pathogen recognition receptors or by epigenetic, transcriptional, and post-transcriptional effects. Furthermore, differentially expressed lncRNAs may be employed as prognostic and diagnostic biomarkers for viral diseases. Here, we summarize the current knowledge of lncRNAs and their functions in viral infections with a specific focus on host-virus responses. In addition, the potential implications of lncRNAs in severe acute respiratory syndrome coronavirus 2 will be discussed. © 2020 John Wiley & Sons Ltd.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
30303 - Infectious Diseases
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2021
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Reviews in Medical Virology
ISSN
1052-9276
e-ISSN
—
Svazek periodika
31
Číslo periodika v rámci svazku
4
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
12
Strana od-do
1-12
Kód UT WoS článku
000592892100001
EID výsledku v databázi Scopus
2-s2.0-85096854275