GENOTOXIC RISK OF PROFESSIONAL EXPOSURE IN IRON INDUSTRY

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F64628299%3A_____%2F01%3A00004777" target="_blank" >RIV/64628299:_____/01:00004777 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

GENOTOXIC RISK OF PROFESSIONAL EXPOSURE IN IRON INDUSTRY

Popis výsledku v původním jazyce

Metallurgy is a priority branch in the industrial agglomeration of Ostrava but it can negatively influence both environment and health status of the whole population. Epidemiological studies have demonstrated that work in ironworks is related to an , increased risk of lung cancer and perhaps leucaemia, stomach and urinary cancer resulting from a possible exposure to polycyclic aromatic hydrocarbons (PAHs), Cr, Ni, asbestos, formaldehyde and furanes. Therefore this study was aimed at , bjectivization ofthe influence of exposure of professionally exposed workers (specifically workforce of blast furnaces) to genotoxic substances in metallurgical plants located in the Ostrava city area. We monitored personal exposure to PAHs , together with biomarkers ofexposure (mutagenic metabolites in urine of the followed up persons using Ames test) and biomarkers of the effect of genotoxic substances (aberrant cells levels using cytogenetic analysis of peripheral blood lymphocytes.

Název v anglickém jazyce

GENOTOXIC RISK OF PROFESSIONAL EXPOSURE IN IRON INDUSTRY

Popis výsledku anglicky

Metallurgy is a priority branch in the industrial agglomeration of Ostrava but it can negatively influence both environment and health status of the whole population. Epidemiological studies have demonstrated that work in ironworks is related to an , increased risk of lung cancer and perhaps leucaemia, stomach and urinary cancer resulting from a possible exposure to polycyclic aromatic hydrocarbons (PAHs), Cr, Ni, asbestos, formaldehyde and furanes. Therefore this study was aimed at , bjectivization ofthe influence of exposure of professionally exposed workers (specifically workforce of blast furnaces) to genotoxic substances in metallurgical plants located in the Ostrava city area. We monitored personal exposure to PAHs , together with biomarkers ofexposure (mutagenic metabolites in urine of the followed up persons using Ames test) and biomarkers of the effect of genotoxic substances (aberrant cells levels using cytogenetic analysis of peripheral blood lymphocytes.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FM - Hygiena

OECD FORD obor

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Projekt

<a href="/cs/project/NJ6140" target="_blank" >NJ6140: Studium rizika genotoxických faktorů v provozech hutnictví železa při použití furanových pryskyřic - odhad expozice</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2001

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Epidemiology

ISSN

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e-ISSN

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Svazek periodika

12

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

1

Strana od-do

"S60"

Kód UT WoS článku

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EID výsledku v databázi Scopus

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