The treatment of HSV1 ocular infections using quantitative real-time PCR results

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F10%3A%230000981" target="_blank" >RIV/65269705:_____/10:#0000981 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/12:00061211

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The treatment of HSV1 ocular infections using quantitative real-time PCR results

Popis výsledku v původním jazyce

Herpes stromal keratitis is a serious condition and the most frequent cause of unilateral blindness. The real-time PCR is an accurate and fast diagnostic method for an analysis of infectious agents causing keratitis and keratouveitis. The aim of the study was to assess the relationship between clinical symptoms, treatment efficacy monitoring and viral quantity in corneal swabs determined by quantitative real-time PCR method. The real-time PCR method was used as well for the detection of other viral eyepathogens. Methods: a total of 212 patients (136 male and 76 female) suspect of having herpes simplex virus (HSV) keratitis or keratouveitis were included in the study. The detection and quantitative analysis of the viral DNA was performed using the EliGene HSV1 RT kit and the result was correlated with the clinical picture of the disease.

Název v anglickém jazyce

The treatment of HSV1 ocular infections using quantitative real-time PCR results

Popis výsledku anglicky

Herpes stromal keratitis is a serious condition and the most frequent cause of unilateral blindness. The real-time PCR is an accurate and fast diagnostic method for an analysis of infectious agents causing keratitis and keratouveitis. The aim of the study was to assess the relationship between clinical symptoms, treatment efficacy monitoring and viral quantity in corneal swabs determined by quantitative real-time PCR method. The real-time PCR method was used as well for the detection of other viral eyepathogens. Methods: a total of 212 patients (136 male and 76 female) suspect of having herpes simplex virus (HSV) keratitis or keratouveitis were included in the study. The detection and quantitative analysis of the viral DNA was performed using the EliGene HSV1 RT kit and the result was correlated with the clinical picture of the disease.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FF - ORL, oftalmologie, stomatologie

OECD FORD obor

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Projekt

<a href="/cs/project/NR8507" target="_blank" >NR8507: DNA diagnostika bakteriálních a virových zánětů rohovky</a><br>

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta ophthalmologica

ISSN

1755-375X

e-ISSN

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Svazek periodika

88

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

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Kód UT WoS článku

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EID výsledku v databázi Scopus

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