Intraindividual variability of homocysteine and related thiolsn concentrations in follicular fluid
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F11%3A%230001288" target="_blank" >RIV/65269705:_____/11:#0001288 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1007/s10815-011-9606-9" target="_blank" >http://dx.doi.org/10.1007/s10815-011-9606-9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10815-011-9606-9" target="_blank" >10.1007/s10815-011-9606-9</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Intraindividual variability of homocysteine and related thiolsn concentrations in follicular fluid
Popis výsledku v původním jazyce
To determine intraindividual variability in concentrations of homocysteine and related thiols in follicular fluids of particular follicles after ovarian stimulation and assess the differences between follicles with/or without oocytes. Methods HPLC-FD analysis of plasma and follicular fluid cysteine, homocysteine, cysteinylglycine and glutathione in women undergoing IVF. In blood plasma, the homocysteine, cysteine, and cysteinylglycine concentrations decreased significantly during stimulation with rec FSH (p<0.001). We found significant differences in concentrations of cysteine and glutathione between follicles with or without retrieved oocytes. High intraindividual variability in concentrations of thiols was determined. The concentration variability ofthiols between single follicles is very high and we recommend mean at least from 3 follicles with/or without oocytes for characterization of each woman. It is the best to examine individual follicles for further research and analysis of
Název v anglickém jazyce
Intraindividual variability of homocysteine and related thiolsn concentrations in follicular fluid
Popis výsledku anglicky
To determine intraindividual variability in concentrations of homocysteine and related thiols in follicular fluids of particular follicles after ovarian stimulation and assess the differences between follicles with/or without oocytes. Methods HPLC-FD analysis of plasma and follicular fluid cysteine, homocysteine, cysteinylglycine and glutathione in women undergoing IVF. In blood plasma, the homocysteine, cysteine, and cysteinylglycine concentrations decreased significantly during stimulation with rec FSH (p<0.001). We found significant differences in concentrations of cysteine and glutathione between follicles with or without retrieved oocytes. High intraindividual variability in concentrations of thiols was determined. The concentration variability ofthiols between single follicles is very high and we recommend mean at least from 3 follicles with/or without oocytes for characterization of each woman. It is the best to examine individual follicles for further research and analysis of
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
FK - Gynekologie a porodnictví
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/NS9661" target="_blank" >NS9661: Vliv metabolismu homocysteinu na poruchy plodnosti.</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2011
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Journal of Assisted Reproduction and Genetics
ISSN
1058-0468
e-ISSN
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Svazek periodika
28
Číslo periodika v rámci svazku
9
Stát vydavatele periodika
DE - Spolková republika Německo
Počet stran výsledku
6
Strana od-do
863-868
Kód UT WoS článku
000294808400014
EID výsledku v databázi Scopus
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