Umbilical cord blood and maternal visfatin (PBEF/NAMPT) concentrations in preterm birth with and without preterm premature rupture of membranes
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F18%3A00068523" target="_blank" >RIV/65269705:_____/18:00068523 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00216224:14110/18:00102133
Výsledek na webu
<a href="http://dx.doi.org/10.1080/14767058.2017.1328493" target="_blank" >http://dx.doi.org/10.1080/14767058.2017.1328493</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/14767058.2017.1328493" target="_blank" >10.1080/14767058.2017.1328493</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Umbilical cord blood and maternal visfatin (PBEF/NAMPT) concentrations in preterm birth with and without preterm premature rupture of membranes
Popis výsledku v původním jazyce
Objectives: The aim of the study is to investigate differences in visfatin concentrations between mothers with term and preterm birth (PTB) and between mothers who delivered within seven days and after more than seven days following admission for PTB/preterm premature rupture of membranes (PPROMs).Methods: Maternal peripheral blood and cord blood were collected from 56 mothers with PTB (31 with PPROM) and 71 mothers with term delivery (three with PPROM).Results: Maternal visfatin concentration was significantly higher for given gestational age in PTBs compared to term deliveries (p=.021) and also in mothers who delivered within seven days after admission for PTB or PPROM, compared to those who delivered after more than seven days (p=.027; p=.039). Cord blood visfatin concentration was found to be decreased in preterm compared to term infants (p=.007).Conclusions: Visfatin in both maternal and fetal circulation may play an important role in the pathogenesis of PTB/PPROM and could be used to distinguish between women who will deliver in a short period of time after clinical presentation of PTB/PPROM and those who deliver later. Nevertheless, additional research is necessary in order to identify its direct involvement in PTB/PPROM.
Název v anglickém jazyce
Umbilical cord blood and maternal visfatin (PBEF/NAMPT) concentrations in preterm birth with and without preterm premature rupture of membranes
Popis výsledku anglicky
Objectives: The aim of the study is to investigate differences in visfatin concentrations between mothers with term and preterm birth (PTB) and between mothers who delivered within seven days and after more than seven days following admission for PTB/preterm premature rupture of membranes (PPROMs).Methods: Maternal peripheral blood and cord blood were collected from 56 mothers with PTB (31 with PPROM) and 71 mothers with term delivery (three with PPROM).Results: Maternal visfatin concentration was significantly higher for given gestational age in PTBs compared to term deliveries (p=.021) and also in mothers who delivered within seven days after admission for PTB or PPROM, compared to those who delivered after more than seven days (p=.027; p=.039). Cord blood visfatin concentration was found to be decreased in preterm compared to term infants (p=.007).Conclusions: Visfatin in both maternal and fetal circulation may play an important role in the pathogenesis of PTB/PPROM and could be used to distinguish between women who will deliver in a short period of time after clinical presentation of PTB/PPROM and those who deliver later. Nevertheless, additional research is necessary in order to identify its direct involvement in PTB/PPROM.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
30214 - Obstetrics and gynaecology
Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
N - Vyzkumna aktivita podporovana z neverejnych zdroju
Ostatní
Rok uplatnění
2018
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
ISSN
1476-7058
e-ISSN
—
Svazek periodika
31
Číslo periodika v rámci svazku
14
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
8
Strana od-do
1811-1818
Kód UT WoS článku
000430732700001
EID výsledku v databázi Scopus
2-s2.0-85019670482