C-reactive protein as predictor of anastomotic complications after minimally invasive oesophagectomy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F19%3A00070514" target="_blank" >RIV/65269705:_____/19:00070514 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/19:00108939

Výsledek na webu

<a href="http://www.journalofmas.com/article.asp?issn=0972-9941;year=2019;volume=15;issue=1;spage=46;epage=50;aulast=Prochazka" target="_blank" >http://www.journalofmas.com/article.asp?issn=0972-9941;year=2019;volume=15;issue=1;spage=46;epage=50;aulast=Prochazka</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4103/jmas.JMAS_254_17" target="_blank" >10.4103/jmas.JMAS_254_17</a>

Jazyk výsledku

angličtina

Název v původním jazyce

C-reactive protein as predictor of anastomotic complications after minimally invasive oesophagectomy

Popis výsledku v původním jazyce

Background: Anastomotic leaks after oesophagectomy with tabularised stomach replacement are a significant factor in post-operative mortality and morbidity. Early detection and treatment of this complication allow for improving operative and oncological results. When assessing laboratory values u elevation of inflammatory parameters u complicated interpretation is an issue (systemic inflammatory response syndrome, surgical versus non-surgical complication). Results studying the relationship between C-reactive protein (CRP) and complications following oesophagectomies are inconsistent. The aim of our work was to find relationships between the development of post-operative CRP values and the occurrence of anastomotic complications following minimally invasive oesophagectomy (MIE). Materials and Methods: Analysis of the relationship between CRP values and the occurrence of anastomotic complications or the necessity of reoperation following oesophagectomy with tabularised stomach replacement and cervical anastomosis performed using thoracoscopy and laparoscopy in a group of patients operated on for malignancies at our department between 2012 and 2015. Results: A significant difference was found in average CRP values on the 5(th) day and 7(th) day following operation between patients with and without leaks (233 mg/l vs. 122.8 mg/l P = 0.003, respectively 208.9 mg/l vs. 121.3 mg/l P = 0.014). However, on the 5(th) day, the leak was clinically apparent only in one case out of 11 leaks. A significant difference in CRP values on the 5(th) day was found between patients who needed revision surgery and patients without revision surgery (294 mg/l vs. 133.5 mg/l P = 0.01). Conclusions: Patients after MIE with tabularised stomach replacement and cervical anastomosis complicated by anastomotic leaks or with the necessity for reoperation had a significantly higher CRP values on the 5(th) day following operation than patients without complications, regardless of the presence of clinical signs of leaks.

Název v anglickém jazyce

C-reactive protein as predictor of anastomotic complications after minimally invasive oesophagectomy

Popis výsledku anglicky

Background: Anastomotic leaks after oesophagectomy with tabularised stomach replacement are a significant factor in post-operative mortality and morbidity. Early detection and treatment of this complication allow for improving operative and oncological results. When assessing laboratory values u elevation of inflammatory parameters u complicated interpretation is an issue (systemic inflammatory response syndrome, surgical versus non-surgical complication). Results studying the relationship between C-reactive protein (CRP) and complications following oesophagectomies are inconsistent. The aim of our work was to find relationships between the development of post-operative CRP values and the occurrence of anastomotic complications following minimally invasive oesophagectomy (MIE). Materials and Methods: Analysis of the relationship between CRP values and the occurrence of anastomotic complications or the necessity of reoperation following oesophagectomy with tabularised stomach replacement and cervical anastomosis performed using thoracoscopy and laparoscopy in a group of patients operated on for malignancies at our department between 2012 and 2015. Results: A significant difference was found in average CRP values on the 5(th) day and 7(th) day following operation between patients with and without leaks (233 mg/l vs. 122.8 mg/l P = 0.003, respectively 208.9 mg/l vs. 121.3 mg/l P = 0.014). However, on the 5(th) day, the leak was clinically apparent only in one case out of 11 leaks. A significant difference in CRP values on the 5(th) day was found between patients who needed revision surgery and patients without revision surgery (294 mg/l vs. 133.5 mg/l P = 0.01). Conclusions: Patients after MIE with tabularised stomach replacement and cervical anastomosis complicated by anastomotic leaks or with the necessity for reoperation had a significantly higher CRP values on the 5(th) day following operation than patients without complications, regardless of the presence of clinical signs of leaks.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30212 - Surgery

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Minimal Access Surgery

ISSN

0972-9941

e-ISSN

—

Svazek periodika

15

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

IN - Indická republika

Počet stran výsledku

5

Strana od-do

46-50

Kód UT WoS článku

000453258200009

EID výsledku v databázi Scopus

2-s2.0-85058653254