Ileocaecal Crohn’s disease and familial adenomatous polyposis in one patient – a case report

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F19%3A00070919" target="_blank" >RIV/65269705:_____/19:00070919 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/19:00110075

Výsledek na webu

<a href="http://pdfs.semanticscholar.org/9298/52ea22c5b3383c63ee7ad5d843d14d00379a.pdf" target="_blank" >http://pdfs.semanticscholar.org/9298/52ea22c5b3383c63ee7ad5d843d14d00379a.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.14735/amgh201946" target="_blank" >10.14735/amgh201946</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Ileocaecal Crohn’s disease and familial adenomatous polyposis in one patient – a case report

Popis výsledku v původním jazyce

Crohn&apos;s disease (CD) and familial adenomatous polyposis (FAP) are two different diseases that both affect the gastrointestinal tract. FAP is an autosomal dominant inherited disease; however, the aetiology of CD is still unknown and is supposed to be multifactorial (genetics, environment, immune state, microbiom). The therapy of these two diseases differs as well. The ultimate solution for FAP is surgery (colectomy or proctocolectomy). On the other hand, CD can be treated either conservatively or surgically. Generally, in cases of bowel resection, the alternative of gastrointestinal tract restoration has to be considered. This decision is more challenging in patients diagnosed with both diseases (CD and FAP). We present the case of a young female with FAP who was diagnosed with active CD in the ileocaecal region. Due to multiple large colon polyps and a stenotic terminal ileum, she was indicated for surgery (colectomy with terminal ileostomy and terminal ileum resection). Subsequently, an ileorectal anastomosis was constructed. In further text, we also discuss other bowel restoration solutions, such as ileal pouch-anal anastomosis and abdominoperineal resection with terminal ileostomy.

Název v anglickém jazyce

Ileocaecal Crohn’s disease and familial adenomatous polyposis in one patient – a case report

Popis výsledku anglicky

Crohn&apos;s disease (CD) and familial adenomatous polyposis (FAP) are two different diseases that both affect the gastrointestinal tract. FAP is an autosomal dominant inherited disease; however, the aetiology of CD is still unknown and is supposed to be multifactorial (genetics, environment, immune state, microbiom). The therapy of these two diseases differs as well. The ultimate solution for FAP is surgery (colectomy or proctocolectomy). On the other hand, CD can be treated either conservatively or surgically. Generally, in cases of bowel resection, the alternative of gastrointestinal tract restoration has to be considered. This decision is more challenging in patients diagnosed with both diseases (CD and FAP). We present the case of a young female with FAP who was diagnosed with active CD in the ileocaecal region. Due to multiple large colon polyps and a stenotic terminal ileum, she was indicated for surgery (colectomy with terminal ileostomy and terminal ileum resection). Subsequently, an ileorectal anastomosis was constructed. In further text, we also discuss other bowel restoration solutions, such as ileal pouch-anal anastomosis and abdominoperineal resection with terminal ileostomy.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

30219 - Gastroenterology and hepatology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Gastroenterologie a hepatologie

ISSN

1804-7874

e-ISSN

—

Svazek periodika

73

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

46-51

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85065527954