Effect of goal-directed fluid management guided by non-invasive device on incidence of postoperative complications in neurosurgery A protocol for pilot study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F21%3A00074786" target="_blank" >RIV/65269705:_____/21:00074786 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/21:00122355

Výsledek na webu

<a href="https://journals.lww.com/md-cases/Fulltext/2021/09000/Effect_of_goal_directed_fluid_management_guided_by.6.aspx" target="_blank" >https://journals.lww.com/md-cases/Fulltext/2021/09000/Effect_of_goal_directed_fluid_management_guided_by.6.aspx</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/MD9.0000000000000142" target="_blank" >10.1097/MD9.0000000000000142</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Effect of goal-directed fluid management guided by non-invasive device on incidence of postoperative complications in neurosurgery A protocol for pilot study

Popis výsledku v původním jazyce

Introduction: Goal-directed hemodynamic therapy aims to reduce the incidence of postoperative complications in patients undergoing surgical procedures. Optimal preload is mandatory to achieve adequate cardiac output and oxygen supply to organs and tissues. Neurosurgical patients are at risk of inadequate preload, decreased blood flow and reduced oxygen delivery, all of which can lead to organ dysfunction. Current knowledge regarding the effect of fluid management on patient-orientated outcomes in neurosurgery is limited. Therefore, this study aims to compare the safety and feasibility of goal-directed therapy with standard management in patients undergoing neurosurgical procedures. Methods and analysis: Patients undergoing neurosurgical operation will be randomised into two groups. Therapy in the first group of patients will be guided by standard perioperative monitoring. In the second group, perioperative therapy will be guided using non-invasive hemodynamic monitoring in addition to standard monitoring. Administration of fluids and vasoactive drugs will depend on the assessment of stroke volume variation and cardiac index. The safety of goal-directed hemodynamic therapy protocol will be assessed by comparing incidences of adverse events between groups.

Název v anglickém jazyce

Effect of goal-directed fluid management guided by non-invasive device on incidence of postoperative complications in neurosurgery A protocol for pilot study

Popis výsledku anglicky

Introduction: Goal-directed hemodynamic therapy aims to reduce the incidence of postoperative complications in patients undergoing surgical procedures. Optimal preload is mandatory to achieve adequate cardiac output and oxygen supply to organs and tissues. Neurosurgical patients are at risk of inadequate preload, decreased blood flow and reduced oxygen delivery, all of which can lead to organ dysfunction. Current knowledge regarding the effect of fluid management on patient-orientated outcomes in neurosurgery is limited. Therefore, this study aims to compare the safety and feasibility of goal-directed therapy with standard management in patients undergoing neurosurgical procedures. Methods and analysis: Patients undergoing neurosurgical operation will be randomised into two groups. Therapy in the first group of patients will be guided by standard perioperative monitoring. In the second group, perioperative therapy will be guided using non-invasive hemodynamic monitoring in addition to standard monitoring. Administration of fluids and vasoactive drugs will depend on the assessment of stroke volume variation and cardiac index. The safety of goal-directed hemodynamic therapy protocol will be assessed by comparing incidences of adverse events between groups.

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

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OECD FORD obor

30200 - Clinical medicine

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Medicine: Case Reports and Study Protocols

ISSN

2691-3895

e-ISSN

—

Svazek periodika

2

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

"e0142"

Kód UT WoS článku

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EID výsledku v databázi Scopus

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