Primary percutaneous coronary intervention is appropriate in transient ST-elevation myocardial infarction

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F22%3A00076049" target="_blank" >RIV/65269705:_____/22:00076049 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/22:00124904

Výsledek na webu

<a href="https://biomed.papers.upol.cz/artkey/bio-202202-0009_primary-percutaneous-coronary-intervention-is-appropriate-in-transient-st-elevation-myocardial-infarction.php" target="_blank" >https://biomed.papers.upol.cz/artkey/bio-202202-0009_primary-percutaneous-coronary-intervention-is-appropriate-in-transient-st-elevation-myocardial-infarction.php</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2021.005" target="_blank" >10.5507/bp.2021.005</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Primary percutaneous coronary intervention is appropriate in transient ST-elevation myocardial infarction

Popis výsledku v původním jazyce

Introduction. Reperfusion therapy by primary percutaneous coronary intervention (PPCI) is generally indicated in patients suffering from acute myocardial infarction (MI) with ST-segment elevation (STEMI). Prior to hospital admission, full ST-segment resolution (fSTR) may occur. Optimal management of such patients with transient STEMI (TSTEMI) is potentially challenging. Our aim was to evaluate the hypothesis that in TSTEMI patients, patency of infarct related artery (IRA) is achieved before PPCI, and to compare the outcome of TSTEMI and STEMI patients during a prolonged follow-up. Material and Methods. Three hundred consecutive adult STEMI patients were referred to catheterization laboratory. In all patients, standard 12 lead ECGs were obtained both at the time of the first medical contact, and on catheterization laboratory admission. Results. TSTEMI occurred in 20 patients (6.7%). Despite fSTR (isoelectric ST segment), occluded IRA was found in 5 of these patients (25%). Pre-PPCI TIMI flow grade 2 was found in 6 TSTEMI patients (30%). Troponin T value at 24 h after symptom onset was lower in the TSTEMI group (1.8 +/- 2.5 mg/L vs. 3.6 +/- 3.5 mg/L, P=0.008). These patients also had a lower value of brain natriuretic peptide (156.3 +/- 119.5 ng/L vs. 438.5 +/- 429.0 ng/L, P&lt;0.001) and higher left ventricular ejection fraction (59.9 +/- 6.3% vs. 51.6 +/- 10.2%, P&lt;0.001). All patients were followed for a median of 5.6 years during which the overall survival did not differ between the TSTEMI and STEMI groups. Conclusion. Primary PCI is strongly recommended in TSTEMI patients because of a relatively high incidence of occluded infarct related arteries. The rate of patients with TSTEMI is relatively low.

Název v anglickém jazyce

Primary percutaneous coronary intervention is appropriate in transient ST-elevation myocardial infarction

Popis výsledku anglicky

Introduction. Reperfusion therapy by primary percutaneous coronary intervention (PPCI) is generally indicated in patients suffering from acute myocardial infarction (MI) with ST-segment elevation (STEMI). Prior to hospital admission, full ST-segment resolution (fSTR) may occur. Optimal management of such patients with transient STEMI (TSTEMI) is potentially challenging. Our aim was to evaluate the hypothesis that in TSTEMI patients, patency of infarct related artery (IRA) is achieved before PPCI, and to compare the outcome of TSTEMI and STEMI patients during a prolonged follow-up. Material and Methods. Three hundred consecutive adult STEMI patients were referred to catheterization laboratory. In all patients, standard 12 lead ECGs were obtained both at the time of the first medical contact, and on catheterization laboratory admission. Results. TSTEMI occurred in 20 patients (6.7%). Despite fSTR (isoelectric ST segment), occluded IRA was found in 5 of these patients (25%). Pre-PPCI TIMI flow grade 2 was found in 6 TSTEMI patients (30%). Troponin T value at 24 h after symptom onset was lower in the TSTEMI group (1.8 +/- 2.5 mg/L vs. 3.6 +/- 3.5 mg/L, P=0.008). These patients also had a lower value of brain natriuretic peptide (156.3 +/- 119.5 ng/L vs. 438.5 +/- 429.0 ng/L, P&lt;0.001) and higher left ventricular ejection fraction (59.9 +/- 6.3% vs. 51.6 +/- 10.2%, P&lt;0.001). All patients were followed for a median of 5.6 years during which the overall survival did not differ between the TSTEMI and STEMI groups. Conclusion. Primary PCI is strongly recommended in TSTEMI patients because of a relatively high incidence of occluded infarct related arteries. The rate of patients with TSTEMI is relatively low.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30100 - Basic medicine

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedical papers - Olomouc

ISSN

1213-8118

e-ISSN

1804-7521

Svazek periodika

166

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

180-186

Kód UT WoS článku

000731339500001

EID výsledku v databázi Scopus

2-s2.0-85130643694