Ventilator-Associated Pneumonia Prevention in Pediatric Patients: Narrative Review

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F22%3A00076457" target="_blank" >RIV/65269705:_____/22:00076457 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/22:00127624

Výsledek na webu

<a href="https://www.mdpi.com/2227-9067/9/10/1540" target="_blank" >https://www.mdpi.com/2227-9067/9/10/1540</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/children9101540" target="_blank" >10.3390/children9101540</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Ventilator-Associated Pneumonia Prevention in Pediatric Patients: Narrative Review

Popis výsledku v původním jazyce

Ventilator-associated pneumonia (VAP), one of the most common healthcare-associated infections in intensive care settings, is associated with significant morbidity and mortality. VAP is diagnosed in &gt;10% of patients on mechanical ventilation, incidence rising with number of ventilator days. In recent decades, the pathophysiology of VAP, VAP risk factors and treatment have been extensively studied. In critically ill pediatric patients, mechanical issues such as insufficient tightness of the ventilator circuit (mainly due to historically based preference of uncuffed tubes) and excessive humidity in the circuit are both significant risk factors of VAP development. Protocol-based approaches to critically ill patients on mechanical ventilation, closed suctioning, upper body position, enteral feeding and selective gastric acid suppression medication have a beneficial effect on VAP incidence. In recent decades, cuffed tubes applied to the whole spectrum of critically ill pediatric patients (except neonates &lt;2700 g of weight), together with cuff-oriented nursing care including proper cuff-pressure (&lt;20 cm H2O) management and the use of specialized tracheal tubes with subglottic suction ports combined with close infraglottic tracheal suctioning, have been implemented. The aim of this review was to summarize the current evidence-based knowledge about the pathophysiology, risk factors, diagnosis, treatment and prevention of VAP in clinically oriented settings.

Název v anglickém jazyce

Ventilator-Associated Pneumonia Prevention in Pediatric Patients: Narrative Review

Popis výsledku anglicky

Ventilator-associated pneumonia (VAP), one of the most common healthcare-associated infections in intensive care settings, is associated with significant morbidity and mortality. VAP is diagnosed in &gt;10% of patients on mechanical ventilation, incidence rising with number of ventilator days. In recent decades, the pathophysiology of VAP, VAP risk factors and treatment have been extensively studied. In critically ill pediatric patients, mechanical issues such as insufficient tightness of the ventilator circuit (mainly due to historically based preference of uncuffed tubes) and excessive humidity in the circuit are both significant risk factors of VAP development. Protocol-based approaches to critically ill patients on mechanical ventilation, closed suctioning, upper body position, enteral feeding and selective gastric acid suppression medication have a beneficial effect on VAP incidence. In recent decades, cuffed tubes applied to the whole spectrum of critically ill pediatric patients (except neonates &lt;2700 g of weight), together with cuff-oriented nursing care including proper cuff-pressure (&lt;20 cm H2O) management and the use of specialized tracheal tubes with subglottic suction ports combined with close infraglottic tracheal suctioning, have been implemented. The aim of this review was to summarize the current evidence-based knowledge about the pathophysiology, risk factors, diagnosis, treatment and prevention of VAP in clinically oriented settings.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30209 - Paediatrics

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

CHILDREN-BASEL

ISSN

2227-9067

e-ISSN

2227-9067

Svazek periodika

9

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

12

Strana od-do

1540

Kód UT WoS článku

000874238800001

EID výsledku v databázi Scopus

2-s2.0-85140637889