Current Opinions on Optimal Management of Basilar Artery Occlusion: After the BEST of BASICS Survey

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F22%3A00077421" target="_blank" >RIV/65269705:_____/22:00077421 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/22:00128866

Výsledek na webu

<a href="https://www.ahajournals.org/doi/epdf/10.1161/SVIN.122.000538" target="_blank" >https://www.ahajournals.org/doi/epdf/10.1161/SVIN.122.000538</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1161/SVIN.122.000538" target="_blank" >10.1161/SVIN.122.000538</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Current Opinions on Optimal Management of Basilar Artery Occlusion: After the BEST of BASICS Survey

Popis výsledku v původním jazyce

BACKGROUND:The best management of basilar artery occlusion (BAO) remains uncertain. The BASICS (Basilar Artery InternationalCooperation Study) and the BEST (Basilar Artery Occlusion Endovascular Intervention Versus Standard Medical Treatment)trials reported neutral results. We sought to understand physicians&apos; approaches to BAOs and whether further BAO randomizedcontrolled trials were warranted.METHODS:We conducted an online international survey from January to March 2022 to stroke neurologists and neurointerven-tionalists. Survey questions were designed to examine clinical and imaging parameters under which clinicians would offer (orrescind) a patient with BAO to endovascular therapy (EVT) or best medical management versus enrollment into a randomizedclinical trial.RESULTS:Of&gt;3002 invited participants, 1245 responded (41.4% response rate) from 73 countries, including 54.7% strokeneurologists and 43.6% neurointerventionalists. More than 95% of respondents would offer EVT to patients with BAO, albeitin various clinical circumstances. There were 70.0% of respondents who indicated that the BASICS and BEST trials did notchange their practice. Only 22.1% of respondents would perform EVT according to anterior circulation occlusion criteria. Theselection of patients for BAO EVT by clinical severity, timing, and imaging modality differed according to geography, specialty,and country income level. Over 80% of respondents agreed that further randomized clinical trials for BAO were warranted.Moreover, 45.6% of respondents indicated they would find it acceptable to enroll all trial-eligible patients into the medical armof a BAO trial, whereas 26.3% would not enroll.CONCLUSION:Most stroke physicians continue to believe in the efficacy of EVT in selected patients with BAO in spite of BEST andBASICS. There is no consensus on which selection criteria to use, and few clinicians would use anterior circulation occlusioncriteria for BAOs. Further randomized clinical trials for BAO are warranted.

Název v anglickém jazyce

Current Opinions on Optimal Management of Basilar Artery Occlusion: After the BEST of BASICS Survey

Popis výsledku anglicky

BACKGROUND:The best management of basilar artery occlusion (BAO) remains uncertain. The BASICS (Basilar Artery InternationalCooperation Study) and the BEST (Basilar Artery Occlusion Endovascular Intervention Versus Standard Medical Treatment)trials reported neutral results. We sought to understand physicians&apos; approaches to BAOs and whether further BAO randomizedcontrolled trials were warranted.METHODS:We conducted an online international survey from January to March 2022 to stroke neurologists and neurointerven-tionalists. Survey questions were designed to examine clinical and imaging parameters under which clinicians would offer (orrescind) a patient with BAO to endovascular therapy (EVT) or best medical management versus enrollment into a randomizedclinical trial.RESULTS:Of&gt;3002 invited participants, 1245 responded (41.4% response rate) from 73 countries, including 54.7% strokeneurologists and 43.6% neurointerventionalists. More than 95% of respondents would offer EVT to patients with BAO, albeitin various clinical circumstances. There were 70.0% of respondents who indicated that the BASICS and BEST trials did notchange their practice. Only 22.1% of respondents would perform EVT according to anterior circulation occlusion criteria. Theselection of patients for BAO EVT by clinical severity, timing, and imaging modality differed according to geography, specialty,and country income level. Over 80% of respondents agreed that further randomized clinical trials for BAO were warranted.Moreover, 45.6% of respondents indicated they would find it acceptable to enroll all trial-eligible patients into the medical armof a BAO trial, whereas 26.3% would not enroll.CONCLUSION:Most stroke physicians continue to believe in the efficacy of EVT in selected patients with BAO in spite of BEST andBASICS. There is no consensus on which selection criteria to use, and few clinicians would use anterior circulation occlusioncriteria for BAOs. Further randomized clinical trials for BAO are warranted.

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

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OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Stroke: Vascular and Interventional Neurology

ISSN

2694-5746

e-ISSN

2694-5746

Svazek periodika

2

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

14

Strana od-do

"e000538"

Kód UT WoS článku

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EID výsledku v databázi Scopus

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