Comparison of different regimens of short-term antibiotic prophylaxis in transrectal prostate biopsy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F24%3A00079831" target="_blank" >RIV/65269705:_____/24:00079831 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/24:00135562

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0195670124000033?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0195670124000033?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jhin.2023.12.012" target="_blank" >10.1016/j.jhin.2023.12.012</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Comparison of different regimens of short-term antibiotic prophylaxis in transrectal prostate biopsy

Popis výsledku v původním jazyce

Background: Prostate cancer is the most common malignant solid tumour in men aged &gt;70 years and is the second most common cause of death from oncological circumstances. Aim: To evaluate the effect of different short-term prophylactic antibiotic regimens in transrectal prostate biopsy (PB) on the incidence of infectious complications. Methods: Patients who underwent transrectal ultrasound-guided PB between January 2021 and December 2022 were included in the prospective randomized study. According to the regimen of prophylaxis, patients were randomized into three groups: (1) fosfomycin trometamol 3 g, 3 h before the procedure + ciprofloxacin 500 mg, 2 h before the procedure; (2) fosfomycin trometamol 3 g, 3 h before and 24 h after the procedure; (3) ciprofloxacin 500 mg 12, 2 h before the procedure, and 12 h after the procedure. A rectal swab was performed 1-2 weeks before PB to evaluate the culture findings. Complications were evaluated during follow-up visits within one month after PB. Findings: In the monitored period, 605 PBs were performed, and 544 patients met the inclusion criteria (184, 161, and 199 in groups 1, 2, and 3). Infectious complications occurred in 10 cases (1.83%), namely 3, 4, and 3 according to patient groups. There was no statistically significant difference between the individual groups. None of the patients required hospitalization and all were free of symptoms of sepsis. Conclusion: Short-term antibiotic prophylaxis in PB using fosfomycin trometamol, ciprofloxacin, or their combination appears to be effective. Fosfomycin trometamol is a suitable alternative to fluoroquinolone antibiotics. (c) 2024 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Název v anglickém jazyce

Comparison of different regimens of short-term antibiotic prophylaxis in transrectal prostate biopsy

Popis výsledku anglicky

Background: Prostate cancer is the most common malignant solid tumour in men aged &gt;70 years and is the second most common cause of death from oncological circumstances. Aim: To evaluate the effect of different short-term prophylactic antibiotic regimens in transrectal prostate biopsy (PB) on the incidence of infectious complications. Methods: Patients who underwent transrectal ultrasound-guided PB between January 2021 and December 2022 were included in the prospective randomized study. According to the regimen of prophylaxis, patients were randomized into three groups: (1) fosfomycin trometamol 3 g, 3 h before the procedure + ciprofloxacin 500 mg, 2 h before the procedure; (2) fosfomycin trometamol 3 g, 3 h before and 24 h after the procedure; (3) ciprofloxacin 500 mg 12, 2 h before the procedure, and 12 h after the procedure. A rectal swab was performed 1-2 weeks before PB to evaluate the culture findings. Complications were evaluated during follow-up visits within one month after PB. Findings: In the monitored period, 605 PBs were performed, and 544 patients met the inclusion criteria (184, 161, and 199 in groups 1, 2, and 3). Infectious complications occurred in 10 cases (1.83%), namely 3, 4, and 3 according to patient groups. There was no statistically significant difference between the individual groups. None of the patients required hospitalization and all were free of symptoms of sepsis. Conclusion: Short-term antibiotic prophylaxis in PB using fosfomycin trometamol, ciprofloxacin, or their combination appears to be effective. Fosfomycin trometamol is a suitable alternative to fluoroquinolone antibiotics. (c) 2024 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30305 - Occupational health

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Hospital Infection

ISSN

0195-6701

e-ISSN

1532-2939

Svazek periodika

145

Číslo periodika v rámci svazku

MAR 2024

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

83-87

Kód UT WoS článku

001181110700001

EID výsledku v databázi Scopus

2-s2.0-85184011173