aktivityMonte Carlo simulation of PET images for injection dose optimization

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985556%3A_____%2F11%3A00369540" target="_blank" >RIV/67985556:_____/11:00369540 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

aktivityMonte Carlo simulation of PET images for injection dose optimization

Popis výsledku v původním jazyce

When a patient is examined by positron emission tomography, radiotracer dose amount has to be determined. However, the rules used nowadays do not correspond with practical experience. Slim patients are given unnecessary amount of radiotracer and obese patients would need more activity to produce images of sufficient quality. We have built a model of a particular PET scanner and approximated human trunk, which is our region of interest, by a cylindrical model with segments of liver, outer adipose tissueand the rest. We have performed Monte Carlo simulations of PET imaging using the GATE simulation package. Under reasonably simplifying assumptions and for special parameters, we have developed curves, which recommend amount of injected activity based onbody parameters to give PET images of constant quality. The dependence qualitatively differs from the rules used in clinical practice nowadays and the results indicate potential for improvement

Název v anglickém jazyce

aktivityMonte Carlo simulation of PET images for injection dose optimization

Popis výsledku anglicky

When a patient is examined by positron emission tomography, radiotracer dose amount has to be determined. However, the rules used nowadays do not correspond with practical experience. Slim patients are given unnecessary amount of radiotracer and obese patients would need more activity to produce images of sufficient quality. We have built a model of a particular PET scanner and approximated human trunk, which is our region of interest, by a cylindrical model with segments of liver, outer adipose tissueand the rest. We have performed Monte Carlo simulations of PET imaging using the GATE simulation package. Under reasonably simplifying assumptions and for special parameters, we have developed curves, which recommend amount of injected activity based onbody parameters to give PET images of constant quality. The dependence qualitatively differs from the rules used in clinical practice nowadays and the results indicate potential for improvement

Druh

D - Stať ve sborníku

CEP obor

BD - Teorie informace

OECD FORD obor

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Projekt

<a href="/cs/project/1M0572" target="_blank" >1M0572: Data, algoritmy, rozhodování</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Computational Vision and Medical Image Processing: VipIMAGE 2011

ISBN

978-0-415-68395-1

ISSN

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e-ISSN

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Počet stran výsledku

6

Strana od-do

1-6

Název nakladatele

Taylor and Francis

Místo vydání

London

Místo konání akce

Olhao, Algarve

Datum konání akce

12. 10. 2011

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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