Post-vaccination, post-infection and hybrid immunity against severe cases of COVID-19 and long COVID after infection with SARS-CoV-2 Omicron subvariants, Czechia, December 2021 to August 2023
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985556%3A_____%2F24%3A00597828" target="_blank" >RIV/67985556:_____/24:00597828 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00216208:11320/24:10484233 RIV/00216224:14110/24:00137012 RIV/00216208:11120/24:43927495
Výsledek na webu
<a href="https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2024.29.35.2300690" target="_blank" >https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2024.29.35.2300690</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2807/1560-7917.ES.2024.29.35.2300690" target="_blank" >10.2807/1560-7917.ES.2024.29.35.2300690</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Post-vaccination, post-infection and hybrid immunity against severe cases of COVID-19 and long COVID after infection with SARS-CoV-2 Omicron subvariants, Czechia, December 2021 to August 2023
Popis výsledku v původním jazyce
Protective effects of immunity against COVID-19 have been shown to diminish over time at varying speed depending on the source of immunity (infection, vaccination or a combination of both), viral variant, age and other factors. Using national-level data from Czechia, we here wanted to assess the protection afforded by vaccines and/or previous infection against severe COVID requiring oxygen support or long COVID up to 16 August 2023.nProtection provided by the original vaccination series wanes fast but can be prolonged through the administration of booster doses, especially with the updated bivalent mRNA vaccines. Immunity after infection or hybrid immunity (from infection and vaccination) provided significantly better protection, waning more slowly over time. The protective effect of vaccines on the development of long COVID in the infected population was small.nVaccination against COVID-19 remains an effective strategy to prevent a severe course of this illness but recent booster doses are required for a significant protection. Since hybrid immunity provides the strongest protection against severe cases, vaccination can be recommended even to individuals who have recovered from the disease. The protective effect of vaccination against long COVID, once infected, appears small.
Název v anglickém jazyce
Post-vaccination, post-infection and hybrid immunity against severe cases of COVID-19 and long COVID after infection with SARS-CoV-2 Omicron subvariants, Czechia, December 2021 to August 2023
Popis výsledku anglicky
Protective effects of immunity against COVID-19 have been shown to diminish over time at varying speed depending on the source of immunity (infection, vaccination or a combination of both), viral variant, age and other factors. Using national-level data from Czechia, we here wanted to assess the protection afforded by vaccines and/or previous infection against severe COVID requiring oxygen support or long COVID up to 16 August 2023.nProtection provided by the original vaccination series wanes fast but can be prolonged through the administration of booster doses, especially with the updated bivalent mRNA vaccines. Immunity after infection or hybrid immunity (from infection and vaccination) provided significantly better protection, waning more slowly over time. The protective effect of vaccines on the development of long COVID in the infected population was small.nVaccination against COVID-19 remains an effective strategy to prevent a severe course of this illness but recent booster doses are required for a significant protection. Since hybrid immunity provides the strongest protection against severe cases, vaccination can be recommended even to individuals who have recovered from the disease. The protective effect of vaccination against long COVID, once infected, appears small.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10102 - Applied mathematics
Návaznosti výsledku
Projekt
<a href="/cs/project/GF22-10878K" target="_blank" >GF22-10878K: Optimální rozhodování v době pandemie</a><br>
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2024
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Eurosurveillance
ISSN
1025-496X
e-ISSN
1560-7917
Svazek periodika
29
Číslo periodika v rámci svazku
35
Stát vydavatele periodika
FR - Francouzská republika
Počet stran výsledku
10
Strana od-do
2300690
Kód UT WoS článku
001308042700002
EID výsledku v databázi Scopus
2-s2.0-85203081831