Nanostructured materials as substrates for the adhesion, growth, and osteogenic differentiation of bone cells
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F16%3A00458563" target="_blank" >RIV/67985823:_____/16:00458563 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1016/B978-0-323-42862-0.00004-3" target="_blank" >http://dx.doi.org/10.1016/B978-0-323-42862-0.00004-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/B978-0-323-42862-0.00004-3" target="_blank" >10.1016/B978-0-323-42862-0.00004-3</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Nanostructured materials as substrates for the adhesion, growth, and osteogenic differentiation of bone cells
Popis výsledku v původním jazyce
Nanostructured materials, particularly those with hierarchically organized macro-, micro-, and nanostructure, imitating the architecture of the natural bone tissue, are promising materials for construction of bone implants and bone tissue engineering. The nanoscale surface roughness has been unambiguously considered as a factor positively influencing the adhesion, growth, and phenotypic maturation of cells. The explanation is that the nanosized irregularities on a material surface mimic the nanoscale architecture of the native ECM. Materials already used or developed for bone implantation and bone tissue engineering can be divided into two basic groups: materials interacting with cells only on their surface, referred as two-dimensional (2D) materials, and materials enabling the ingrowth of cell into their inner structure, referred as three-dimensional (3D) materials. On 2D surfaces, the nanoscale features can be achieved by two main types of modification: subtractive and additive. Both technologies have been often combined. In 3D materials, nanostructure can be achieved by, for example, reinforcing macro- or microporous and micro- or nanofibrous polymeric scaffolds with ceramic, carbon-based, metal-based, or other nanoparticles. In this chapter, we summarize our experience and the experience of other authors concerning the adhesion, growth, and differentiation of osteogenic cells on 2D and 3D materials containing nanoscale features created by various technologies.
Název v anglickém jazyce
Nanostructured materials as substrates for the adhesion, growth, and osteogenic differentiation of bone cells
Popis výsledku anglicky
Nanostructured materials, particularly those with hierarchically organized macro-, micro-, and nanostructure, imitating the architecture of the natural bone tissue, are promising materials for construction of bone implants and bone tissue engineering. The nanoscale surface roughness has been unambiguously considered as a factor positively influencing the adhesion, growth, and phenotypic maturation of cells. The explanation is that the nanosized irregularities on a material surface mimic the nanoscale architecture of the native ECM. Materials already used or developed for bone implantation and bone tissue engineering can be divided into two basic groups: materials interacting with cells only on their surface, referred as two-dimensional (2D) materials, and materials enabling the ingrowth of cell into their inner structure, referred as three-dimensional (3D) materials. On 2D surfaces, the nanoscale features can be achieved by two main types of modification: subtractive and additive. Both technologies have been often combined. In 3D materials, nanostructure can be achieved by, for example, reinforcing macro- or microporous and micro- or nanofibrous polymeric scaffolds with ceramic, carbon-based, metal-based, or other nanoparticles. In this chapter, we summarize our experience and the experience of other authors concerning the adhesion, growth, and differentiation of osteogenic cells on 2D and 3D materials containing nanoscale features created by various technologies.
Klasifikace
Druh
C - Kapitola v odborné knize
CEP obor
EI - Biotechnologie a bionika
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/GBP108%2F12%2FG108" target="_blank" >GBP108/12/G108: Příprava, modifikace a charakterizace materiálů zářením</a><br>
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2016
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název knihy nebo sborníku
Nanobiomaterials in Hard Tissue Engineering
ISBN
978-0-323-42862-0
Počet stran výsledku
51
Strana od-do
103-153
Počet stran knihy
484
Název nakladatele
Elsevier
Místo vydání
Amsterdam
Kód UT WoS kapitoly
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