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Nanostructured materials as substrates for the adhesion, growth, and osteogenic differentiation of bone cells

Identifikátory výsledku

  • Kód výsledku v IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F16%3A00458563" target="_blank" >RIV/67985823:_____/16:00458563 - isvavai.cz</a>

  • Výsledek na webu

    <a href="http://dx.doi.org/10.1016/B978-0-323-42862-0.00004-3" target="_blank" >http://dx.doi.org/10.1016/B978-0-323-42862-0.00004-3</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/B978-0-323-42862-0.00004-3" target="_blank" >10.1016/B978-0-323-42862-0.00004-3</a>

Alternativní jazyky

  • Jazyk výsledku

    angličtina

  • Název v původním jazyce

    Nanostructured materials as substrates for the adhesion, growth, and osteogenic differentiation of bone cells

  • Popis výsledku v původním jazyce

    Nanostructured materials, particularly those with hierarchically organized macro-, micro-, and nanostructure, imitating the architecture of the natural bone tissue, are promising materials for construction of bone implants and bone tissue engineering. The nanoscale surface roughness has been unambiguously considered as a factor positively influencing the adhesion, growth, and phenotypic maturation of cells. The explanation is that the nanosized irregularities on a material surface mimic the nanoscale architecture of the native ECM. Materials already used or developed for bone implantation and bone tissue engineering can be divided into two basic groups: materials interacting with cells only on their surface, referred as two-dimensional (2D) materials, and materials enabling the ingrowth of cell into their inner structure, referred as three-dimensional (3D) materials. On 2D surfaces, the nanoscale features can be achieved by two main types of modification: subtractive and additive. Both technologies have been often combined. In 3D materials, nanostructure can be achieved by, for example, reinforcing macro- or microporous and micro- or nanofibrous polymeric scaffolds with ceramic, carbon-based, metal-based, or other nanoparticles. In this chapter, we summarize our experience and the experience of other authors concerning the adhesion, growth, and differentiation of osteogenic cells on 2D and 3D materials containing nanoscale features created by various technologies.

  • Název v anglickém jazyce

    Nanostructured materials as substrates for the adhesion, growth, and osteogenic differentiation of bone cells

  • Popis výsledku anglicky

    Nanostructured materials, particularly those with hierarchically organized macro-, micro-, and nanostructure, imitating the architecture of the natural bone tissue, are promising materials for construction of bone implants and bone tissue engineering. The nanoscale surface roughness has been unambiguously considered as a factor positively influencing the adhesion, growth, and phenotypic maturation of cells. The explanation is that the nanosized irregularities on a material surface mimic the nanoscale architecture of the native ECM. Materials already used or developed for bone implantation and bone tissue engineering can be divided into two basic groups: materials interacting with cells only on their surface, referred as two-dimensional (2D) materials, and materials enabling the ingrowth of cell into their inner structure, referred as three-dimensional (3D) materials. On 2D surfaces, the nanoscale features can be achieved by two main types of modification: subtractive and additive. Both technologies have been often combined. In 3D materials, nanostructure can be achieved by, for example, reinforcing macro- or microporous and micro- or nanofibrous polymeric scaffolds with ceramic, carbon-based, metal-based, or other nanoparticles. In this chapter, we summarize our experience and the experience of other authors concerning the adhesion, growth, and differentiation of osteogenic cells on 2D and 3D materials containing nanoscale features created by various technologies.

Klasifikace

  • Druh

    C - Kapitola v odborné knize

  • CEP obor

    EI - Biotechnologie a bionika

  • OECD FORD obor

Návaznosti výsledku

  • Projekt

    <a href="/cs/project/GBP108%2F12%2FG108" target="_blank" >GBP108/12/G108: Příprava, modifikace a charakterizace materiálů zářením</a><br>

  • Návaznosti

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Ostatní

  • Rok uplatnění

    2016

  • Kód důvěrnosti údajů

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Údaje specifické pro druh výsledku

  • Název knihy nebo sborníku

    Nanobiomaterials in Hard Tissue Engineering

  • ISBN

    978-0-323-42862-0

  • Počet stran výsledku

    51

  • Strana od-do

    103-153

  • Počet stran knihy

    484

  • Název nakladatele

    Elsevier

  • Místo vydání

    Amsterdam

  • Kód UT WoS kapitoly