Spike frequency adaptation facilitates the encoding of input gradient in insect olfactory projection neurons

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F23%3A00567073" target="_blank" >RIV/67985823:_____/23:00567073 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1016/j.biosystems.2022.104802" target="_blank" >https://doi.org/10.1016/j.biosystems.2022.104802</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.biosystems.2022.104802" target="_blank" >10.1016/j.biosystems.2022.104802</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Spike frequency adaptation facilitates the encoding of input gradient in insect olfactory projection neurons

Popis výsledku v původním jazyce

The olfactory system in insects has evolved to process the dynamic changes in the concentration of food odors or sex pheromones to localize the nutrients or conspecific mating partners. Experimental studies have suggested that projection neurons (PNs) in insects encode not only the stimulus intensity but also its rate-ofchange (input gradient). In this study, we aim to develop a simple computational model for a PN to understand the mechanism underlying the coding of the rate-of-change information. We show that the spike frequency adaptation is a potential key mechanism for reproducing the phasic response pattern of the PN in Drosophila. We also demonstrate that this adaptation mechanism enables the PN to encode the rate-of-change of the input firing rate. Finally, our model predicts that the PN exhibits the intensity-invariant response for the pulse and ramp odor stimulus. These results suggest that the developed model is useful for investigating the coding principle underlying olfactory information processing in insects.

Název v anglickém jazyce

Spike frequency adaptation facilitates the encoding of input gradient in insect olfactory projection neurons

Popis výsledku anglicky

The olfactory system in insects has evolved to process the dynamic changes in the concentration of food odors or sex pheromones to localize the nutrients or conspecific mating partners. Experimental studies have suggested that projection neurons (PNs) in insects encode not only the stimulus intensity but also its rate-ofchange (input gradient). In this study, we aim to develop a simple computational model for a PN to understand the mechanism underlying the coding of the rate-of-change information. We show that the spike frequency adaptation is a potential key mechanism for reproducing the phasic response pattern of the PN in Drosophila. We also demonstrate that this adaptation mechanism enables the PN to encode the rate-of-change of the input firing rate. Finally, our model predicts that the PN exhibits the intensity-invariant response for the pulse and ramp odor stimulus. These results suggest that the developed model is useful for investigating the coding principle underlying olfactory information processing in insects.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10103 - Statistics and probability

Projekt

<a href="/cs/project/GA20-10251S" target="_blank" >GA20-10251S: Optimalita neuronální komunikace: informačně-teoretický pohled</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biosystems

ISSN

0303-2647

e-ISSN

1872-8324

Svazek periodika

223

Číslo periodika v rámci svazku

January

Stát vydavatele periodika

IE - Irsko

Počet stran výsledku

8

Strana od-do

104802

Kód UT WoS článku

000899830200002

EID výsledku v databázi Scopus

2-s2.0-85142673581