Study of TiO2 Nanoparticle Generation for Follow-up Inhalation Experiments with Laboratory Animals.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985858%3A_____%2F16%3A00463828" target="_blank" >RIV/67985858:_____/16:00463828 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1080/02786826.2016.1224803" target="_blank" >http://dx.doi.org/10.1080/02786826.2016.1224803</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/02786826.2016.1224803" target="_blank" >10.1080/02786826.2016.1224803</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Study of TiO2 Nanoparticle Generation for Follow-up Inhalation Experiments with Laboratory Animals.

Popis výsledku v původním jazyce

A method of long-lasting TiO2 nanoparticle generation was tested for use in follow-up studies of the health impacts of nanoparticles on laboratory animals during several weeks’ long exposure experiments. Nanoparticles were synthesized in an externally heated tube reactor by pyrolysis and oxidation of titanium tetraisopropoxide. Particle production was studied under varying reactor temperature, reactor flow rate, and precursor vapor pressure. A total of 264 h of particle generation were performed in four experimental campaigns using one batch of precursor without an observable decrease of particle production. As a result, particle production with number concentrations high above 1.0 £ 107 #/cm3 and with primary particle sizes well below 50 nm could be achieved in most of the investigated experimental conditions. Maximum of particle mass concentration reached the value 9500 mg/m3, which corresponds with emission rate 29 mg/min. The dependence of nanoparticle production and characteristics on experimental conditions was evaluated and the most suitable parameters for exposure experiments were specified. A comparison of the results with data from the literature shows that the material of the reactor plays a significant role in the process of particle formation.

Název v anglickém jazyce

Study of TiO2 Nanoparticle Generation for Follow-up Inhalation Experiments with Laboratory Animals.

Popis výsledku anglicky

A method of long-lasting TiO2 nanoparticle generation was tested for use in follow-up studies of the health impacts of nanoparticles on laboratory animals during several weeks’ long exposure experiments. Nanoparticles were synthesized in an externally heated tube reactor by pyrolysis and oxidation of titanium tetraisopropoxide. Particle production was studied under varying reactor temperature, reactor flow rate, and precursor vapor pressure. A total of 264 h of particle generation were performed in four experimental campaigns using one batch of precursor without an observable decrease of particle production. As a result, particle production with number concentrations high above 1.0 £ 107 #/cm3 and with primary particle sizes well below 50 nm could be achieved in most of the investigated experimental conditions. Maximum of particle mass concentration reached the value 9500 mg/m3, which corresponds with emission rate 29 mg/min. The dependence of nanoparticle production and characteristics on experimental conditions was evaluated and the most suitable parameters for exposure experiments were specified. A comparison of the results with data from the literature shows that the material of the reactor plays a significant role in the process of particle formation.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CF - Fyzikální chemie a teoretická chemie

OECD FORD obor

—

Projekt

<a href="/cs/project/GBP503%2F12%2FG147" target="_blank" >GBP503/12/G147: Centrum studií toxických vlastností nanočástic</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Aerosol Science and Technology

ISSN

0278-6826

e-ISSN

—

Svazek periodika

50

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

1068-1076

Kód UT WoS článku

000386209700006

EID výsledku v databázi Scopus

2-s2.0-84987642681