MOCVD Iron Oxide Nanoparticle Generation not Only for Follow-Up Inalation Exposure Experiments.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985858%3A_____%2F18%3A00496252" target="_blank" >RIV/67985858:_____/18:00496252 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61388980:_____/18:00496252

Výsledek na webu

<a href="http://hdl.handle.net/11104/0289067" target="_blank" >http://hdl.handle.net/11104/0289067</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

MOCVD Iron Oxide Nanoparticle Generation not Only for Follow-Up Inalation Exposure Experiments.

Popis výsledku v původním jazyce

Iron oxide nanoparticles (NPs) are industrially produced and commercially available and they are also frequently emitted into the environment by iron making plants. In the human body, iron is maintained at homeostatic fairly low level. However, freshly generated iron oxide NPs cause febrile and inflammatory response known as metal fume fever, but the potential in vivo consequences of inhalation of iron oxide NPs from the atmosphere has not yet been investigated. An overview of recent studies evaluating iron oxide NPs cytotoxicity, genotoxicity, developmental toxicity and neurotoxicity was presented by Valdiglesias et al. (2015). Toxicity of iron oxide NPs has been studied both in vitro and in vivo. Exposure chamber for the whole body inhalation experiments with small laboratory animals was constructed at the Institute of Analytical Chemistry of the CAS (Večeřa et al., 2011) and some methods of NPs generation for these experiments were already tested in our laboratory (Moravec et al., 2015. Moravec et al., 2016). In this study we tested a method of long lasting generation of iron oxide NPs by pyrolysis and oxidation of ironIII acetylacetonate (FeAA3).

Název v anglickém jazyce

MOCVD Iron Oxide Nanoparticle Generation not Only for Follow-Up Inalation Exposure Experiments.

Popis výsledku anglicky

Iron oxide nanoparticles (NPs) are industrially produced and commercially available and they are also frequently emitted into the environment by iron making plants. In the human body, iron is maintained at homeostatic fairly low level. However, freshly generated iron oxide NPs cause febrile and inflammatory response known as metal fume fever, but the potential in vivo consequences of inhalation of iron oxide NPs from the atmosphere has not yet been investigated. An overview of recent studies evaluating iron oxide NPs cytotoxicity, genotoxicity, developmental toxicity and neurotoxicity was presented by Valdiglesias et al. (2015). Toxicity of iron oxide NPs has been studied both in vitro and in vivo. Exposure chamber for the whole body inhalation experiments with small laboratory animals was constructed at the Institute of Analytical Chemistry of the CAS (Večeřa et al., 2011) and some methods of NPs generation for these experiments were already tested in our laboratory (Moravec et al., 2015. Moravec et al., 2016). In this study we tested a method of long lasting generation of iron oxide NPs by pyrolysis and oxidation of ironIII acetylacetonate (FeAA3).

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

10511 - Environmental sciences (social aspects to be 5.7)

Projekt

<a href="/cs/project/GBP503%2F12%2FG147" target="_blank" >GBP503/12/G147: Centrum studií toxických vlastností nanočástic</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Sborník XIX. výroční konference České aerosolové společnosti, pp. 44-47

ISBN

978-80-270-4780-2

ISSN

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e-ISSN

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Počet stran výsledku

4

Strana od-do

80-83

Název nakladatele

Česká Aerosolová společnost

Místo vydání

Praha

Místo konání akce

Piešťany

Datum konání akce

25. 10. 2018

Typ akce podle státní příslušnosti

EUR - Evropská akce

Kód UT WoS článku

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