Porphyrin‑silver Nanoparticles Hybrids: Synthesis, Characterization and Antibacterial Activity.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985858%3A_____%2F19%3A00511844" target="_blank" >RIV/67985858:_____/19:00511844 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22310/19:43918749 RIV/60461373:22330/19:43918749

Výsledek na webu

<a href="http://hdl.handle.net/11104/0302091" target="_blank" >http://hdl.handle.net/11104/0302091</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.msec.2019.04.029" target="_blank" >10.1016/j.msec.2019.04.029</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Porphyrin‑silver Nanoparticles Hybrids: Synthesis, Characterization and Antibacterial Activity.

Popis výsledku v původním jazyce

The preparation of light-activated hybrid antibacterial agent combining the porphyrin molecules, bound to the silver nanoparticles (AgNPs) surface is reported. AgNPs were synthesized by N-methyl-2-pyrrolidone-initiated reduction without additional reducing agents. The chemical structure of protoporphyrin IX was modified with the aim to introduce thiol groups. The size distribution and shape features of AgNPs were checked using TEM and HRTEM microscopies. The introduction of thiol groups into the porphyrin was proved by IR spectroscopy. The AgNPs-porphyrin binding was performed in solution and confirmed by fluorescence quenching, Raman spectroscopy and energy-filtered transmission electron microscopy (EFTEM). The antibacterial tests were performed against S. epidermidis and E. coli upon to LED illumination and in the dark. The synergetic effect of AgNPs and porphyrin as well as light activation of the created antibacterial conjugates were observed.

Název v anglickém jazyce

Porphyrin‑silver Nanoparticles Hybrids: Synthesis, Characterization and Antibacterial Activity.

Popis výsledku anglicky

The preparation of light-activated hybrid antibacterial agent combining the porphyrin molecules, bound to the silver nanoparticles (AgNPs) surface is reported. AgNPs were synthesized by N-methyl-2-pyrrolidone-initiated reduction without additional reducing agents. The chemical structure of protoporphyrin IX was modified with the aim to introduce thiol groups. The size distribution and shape features of AgNPs were checked using TEM and HRTEM microscopies. The introduction of thiol groups into the porphyrin was proved by IR spectroscopy. The AgNPs-porphyrin binding was performed in solution and confirmed by fluorescence quenching, Raman spectroscopy and energy-filtered transmission electron microscopy (EFTEM). The antibacterial tests were performed against S. epidermidis and E. coli upon to LED illumination and in the dark. The synergetic effect of AgNPs and porphyrin as well as light activation of the created antibacterial conjugates were observed.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10401 - Organic chemistry

Projekt

<a href="/cs/project/GA17-00885S" target="_blank" >GA17-00885S: Nanostrukturované nosiče na bázi celulózy a jejích derivátů s nastavitelnými vlastnostmi pro tkáňové inženýrství</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Materials Science & Engineering C-Materials for Biological Applications

ISSN

0928-4931

e-ISSN

—

Svazek periodika

102

Číslo periodika v rámci svazku

SEP 2019

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

192-199

Kód UT WoS článku

000472241700020

EID výsledku v databázi Scopus

2-s2.0-85064514066