Controlled anchoring of (phenylureido)sulfonamide-based receptor moieties: an impact of binding site multiplication on complexation properties

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985858%3A_____%2F21%3A00545524" target="_blank" >RIV/67985858:_____/21:00545524 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22310/21:43922618 RIV/60461373:22340/21:43922618

Výsledek na webu

<a href="https://www.mdpi.com/1420-3049/26/18/5670" target="_blank" >https://www.mdpi.com/1420-3049/26/18/5670</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/molecules26185670" target="_blank" >10.3390/molecules26185670</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Controlled anchoring of (phenylureido)sulfonamide-based receptor moieties: an impact of binding site multiplication on complexation properties

Popis výsledku v původním jazyce

The repetition of urea-based binding units within the receptor structure does not only lead to monomer properties multiplication. As confirmed by spectroscopic studies, UV-Vis and 1H-NMR in classical or competitive titration mode, the attachment to a carrier allocates the active moieties to mutual positions predetermining the function of the whole receptor molecule. Bivalent receptors form self-aggregates. Dendritic receptors with low dihydrogen phosphate loadings offer ancooperative complexation mode associated with a positive dendritic effect. In higher dihydrogen phosphate concentrations, the dendritic branches act independently and the binding mode changes to 1:1 anion: complexation site. Despite the anchoring, the dendritic receptors retain the superior efficiency and selectivity of a monomer, paving the way to recyclable receptors, desirable for economic and ecological reasons.

Název v anglickém jazyce

Controlled anchoring of (phenylureido)sulfonamide-based receptor moieties: an impact of binding site multiplication on complexation properties

Popis výsledku anglicky

The repetition of urea-based binding units within the receptor structure does not only lead to monomer properties multiplication. As confirmed by spectroscopic studies, UV-Vis and 1H-NMR in classical or competitive titration mode, the attachment to a carrier allocates the active moieties to mutual positions predetermining the function of the whole receptor molecule. Bivalent receptors form self-aggregates. Dendritic receptors with low dihydrogen phosphate loadings offer ancooperative complexation mode associated with a positive dendritic effect. In higher dihydrogen phosphate concentrations, the dendritic branches act independently and the binding mode changes to 1:1 anion: complexation site. Despite the anchoring, the dendritic receptors retain the superior efficiency and selectivity of a monomer, paving the way to recyclable receptors, desirable for economic and ecological reasons.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10401 - Organic chemistry

Projekt

<a href="/cs/project/GA20-07833S" target="_blank" >GA20-07833S: Nové nanomateriály pro separaci aniontů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Molecules

ISSN

1420-3049

e-ISSN

1420-3049

Svazek periodika

26

Číslo periodika v rámci svazku

18

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

14

Strana od-do

5670

Kód UT WoS článku

000701842500001

EID výsledku v databázi Scopus

2-s2.0-85115403195