Chemical Engineering View on the Silicone Oil Utilization in the Treatment of Retinal Detachment

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985858%3A_____%2F24%3A00600399" target="_blank" >RIV/67985858:_____/24:00600399 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/24:43927662 RIV/00216208:11310/24:10486616 RIV/00064173:_____/24:43927662

Výsledek na webu

<a href="https://hdl.handle.net/11104/0357727" target="_blank" >https://hdl.handle.net/11104/0357727</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/cben.202400090" target="_blank" >10.1002/cben.202400090</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Chemical Engineering View on the Silicone Oil Utilization in the Treatment of Retinal Detachment

Popis výsledku v původním jazyce

Retinal detachment is an acute condition in ophthalmology that needs an immediate surgical management. The treatment requires a replacement of the vitreous with a temporary substitute, usually based on a silicone oil. A certain number of patients experience adverse events during the treatment. It seems this phenomenon is related to the formation of emulsions in the affected eye. These appear macroscopically as heterogeneities resembling small droplets with a patchy occurrence in the vitreous substitute. Their existence represents a major complication that may lead to loss of vision. The heterogeneities are transported to regions of the eye in which they cause irreversible damage. The current state of knowledge describes the phenomenon and recommends certain intervention procedures. Here, specific attention is paid to the chemical engineering aspects of the utilization of silicone oils for the treatment of the retinal detachment. It is very likely that the process of tiny droplet formation leading to the development of emulsions is substantially controlled by the hydrodynamic conditions in the eye. The complexity of this statement is examined in this review text.

Název v anglickém jazyce

Chemical Engineering View on the Silicone Oil Utilization in the Treatment of Retinal Detachment

Popis výsledku anglicky

Retinal detachment is an acute condition in ophthalmology that needs an immediate surgical management. The treatment requires a replacement of the vitreous with a temporary substitute, usually based on a silicone oil. A certain number of patients experience adverse events during the treatment. It seems this phenomenon is related to the formation of emulsions in the affected eye. These appear macroscopically as heterogeneities resembling small droplets with a patchy occurrence in the vitreous substitute. Their existence represents a major complication that may lead to loss of vision. The heterogeneities are transported to regions of the eye in which they cause irreversible damage. The current state of knowledge describes the phenomenon and recommends certain intervention procedures. Here, specific attention is paid to the chemical engineering aspects of the utilization of silicone oils for the treatment of the retinal detachment. It is very likely that the process of tiny droplet formation leading to the development of emulsions is substantially controlled by the hydrodynamic conditions in the eye. The complexity of this statement is examined in this review text.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30207 - Ophthalmology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

ChemBioEng Reviews

ISSN

2196-9744

e-ISSN

2196-9744

Svazek periodika

11

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

11

Strana od-do

e202400090

Kód UT WoS článku

001333966700001

EID výsledku v databázi Scopus

2-s2.0-85206442961