Electrodynamic effects on microtubules

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985882%3A_____%2F15%3A00473515" target="_blank" >RIV/67985882:_____/15:00473515 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Electrodynamic effects on microtubules

Popis výsledku v původním jazyce

Microtubules, polymer tubes of cellular skeleton, are involved in a number of processes servingfor various func-tions. Besides their role in cell mechanics and cell division they also provide enormous substrate for cellular signaling.Here we combine the normal mode analysis of microtubuleswith the electric charge density distribution model of a microtubule. We showinsilicothat each normal mode of a microtubule is accompanied with the high-frequency electro-nmagnetic field which is generated by vibrational movement of the charge. Combination of normal modes gives rise to transient phenomenon which can manifest itself as a pulsed excitation propagating along a microtubule.We speculate that such pulses can play role in cell signaling because they are of different nature than pure electrostatic interaction which is screened out on frequencies of normal modes of microtubules

Název v anglickém jazyce

Electrodynamic effects on microtubules

Popis výsledku anglicky

Microtubules, polymer tubes of cellular skeleton, are involved in a number of processes servingfor various func-tions. Besides their role in cell mechanics and cell division they also provide enormous substrate for cellular signaling.Here we combine the normal mode analysis of microtubuleswith the electric charge density distribution model of a microtubule. We showinsilicothat each normal mode of a microtubule is accompanied with the high-frequency electro-nmagnetic field which is generated by vibrational movement of the charge. Combination of normal modes gives rise to transient phenomenon which can manifest itself as a pulsed excitation propagating along a microtubule.We speculate that such pulses can play role in cell signaling because they are of different nature than pure electrostatic interaction which is screened out on frequencies of normal modes of microtubules

Druh

O - Ostatní výsledky

CEP obor

JA - Elektronika a optoelektronika, elektrotechnika

OECD FORD obor

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Projekt

<a href="/cs/project/GA15-17102S" target="_blank" >GA15-17102S: Radiofrekvenční charakterizace mikrotubulů pomocí mikro- a nanosenzorů</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů