Resolving controversy of unusually high refractive index of a tubulin

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985882%3A_____%2F17%3A00484852" target="_blank" >RIV/67985882:_____/17:00484852 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68378050:_____/17:00484852

Výsledek na webu

<a href="http://dx.doi.org/10.1209/0295-5075/117/38003" target="_blank" >http://dx.doi.org/10.1209/0295-5075/117/38003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1209/0295-5075/117/38003" target="_blank" >10.1209/0295-5075/117/38003</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Resolving controversy of unusually high refractive index of a tubulin

Popis výsledku v původním jazyce

The refractive index of a tubulin is an important parameter underlying fundamental electromagnetic and biophysical properties of microtubules - protein fibers essential for several cell functions including cell division. Yet, the only experimental data available in the current literature show values of the tubulin refractive index (n = 2.36-2.90) which are much higher than what the established theories predict based on the weighted contribution of the polarizability of individual amino acids constituting the protein. To resolve this controversy, we report here modeling and rigorous experimental analysis of the refractive index of a purified tubulin dimer. Our experimental data revealed that the refractive index of the tubulin is n = 1.64 at wavelength 589 nm and 25 degrees C, that is much closer to the values predicted by the established theories than what the earlier experimental data provide

Název v anglickém jazyce

Resolving controversy of unusually high refractive index of a tubulin

Popis výsledku anglicky

The refractive index of a tubulin is an important parameter underlying fundamental electromagnetic and biophysical properties of microtubules - protein fibers essential for several cell functions including cell division. Yet, the only experimental data available in the current literature show values of the tubulin refractive index (n = 2.36-2.90) which are much higher than what the established theories predict based on the weighted contribution of the polarizability of individual amino acids constituting the protein. To resolve this controversy, we report here modeling and rigorous experimental analysis of the refractive index of a purified tubulin dimer. Our experimental data revealed that the refractive index of the tubulin is n = 1.64 at wavelength 589 nm and 25 degrees C, that is much closer to the values predicted by the established theories than what the earlier experimental data provide

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10306 - Optics (including laser optics and quantum optics)

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Europhysics Letters

ISSN

0295-5075

e-ISSN

—

Svazek periodika

117

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

FR - Francouzská republika

Počet stran výsledku

5

Strana od-do

—

Kód UT WoS článku

000401165100001

EID výsledku v databázi Scopus

2-s2.0-85016803852