Proliferace a apoptóza v rané morfogenezi stoličky - hraboš jako model pro odontogenetické studie

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F06%3A00040990" target="_blank" >RIV/67985904:_____/06:00040990 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62157124:16170/06:00000588

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Proliferation and apoptosis in early molar morphogenesis - voles as models in odontogenesis

Popis výsledku v původním jazyce

Proliferation and apoptosis play crucial roles in the development of multicellular organisms. The developing dentition is a suitable model to study proliferation and apoptosis during embryogenesis but has mainly been studied in the mouse. This study aimed to study proliferation and apoptosis in the vole during the early morphogenesis of the first upper molar and compare it to what is known from the mouse. For this purpose, apoptosis and proliferation were investigated using histology and computer-aided3D reconstruction. Mitoses accumulated predominantly in the developing cervical loop. Apoptosis during early odontogenesis showed highly specific spatio-temporal patterns in the dental epithelium. Apoptotic bodies accumulated in the same places as described in the mouse: antemolar vestiges, enamel knot, stalk, and palatally along the whole first molar tooth germ longitudinal axis. Early tooth development of the field vole including apoptosis and mitosis distribution is very similar to th

Název v anglickém jazyce

Proliferation and apoptosis in early molar morphogenesis - voles as models in odontogenesis

Popis výsledku anglicky

Proliferation and apoptosis play crucial roles in the development of multicellular organisms. The developing dentition is a suitable model to study proliferation and apoptosis during embryogenesis but has mainly been studied in the mouse. This study aimed to study proliferation and apoptosis in the vole during the early morphogenesis of the first upper molar and compare it to what is known from the mouse. For this purpose, apoptosis and proliferation were investigated using histology and computer-aided3D reconstruction. Mitoses accumulated predominantly in the developing cervical loop. Apoptosis during early odontogenesis showed highly specific spatio-temporal patterns in the dental epithelium. Apoptotic bodies accumulated in the same places as described in the mouse: antemolar vestiges, enamel knot, stalk, and palatally along the whole first molar tooth germ longitudinal axis. Early tooth development of the field vole including apoptosis and mitosis distribution is very similar to th

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Developmental Biology

ISSN

0214-6282

e-ISSN

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Svazek periodika

50

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

ES - Španělské království

Počet stran výsledku

9

Strana od-do

481-489

Kód UT WoS článku

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EID výsledku v databázi Scopus

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