Alelická variabilita prasečího resistinového (RETN ) genu je asociována s ukládáním tuku u referenční rodiny divoké prase x meishan

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F06%3A00054487" target="_blank" >RIV/67985904:_____/06:00054487 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Allelic variation in porcine resistin (RETN) gene is associated with fatness traits in a Wild Boar x Meishan reference family

Popis výsledku v původním jazyce

Cloning and comparative sequencing of the porcine resistin (RETN) gene and 5? flanking region, located at 64 cM on SSC2, revealed 9 SNPs and 2 indels. A European Wild Boar x Meishan family encompassing 335 F2 animals measured for 46 traits including growth, fat deposition and muscle accretion was scored for a T2094C polymorphism by means of MvaI PCR-RFLP. Two haplotypes (AM157180 and AM157181) segregated in the family while the imprinted QTL in IGF2 was fixed. The founder boar was homozygote MvaI BB while Meishan F0 sows segregated alleles MvaI A and MvaI B. Previous QTL mapping by Lee et al. (2003) did not reveal any QTL for fat accretion in the MYOD - SW395 interval where RETN is located. Association analysis showed that the MvaI A allele of Meishanorigin accompanied by the 1472A allele encoding for 36Ala is associated with higher values for fat deposition traits (fat depth at 10th rib, back fat depth at 13th/14th rib, loin fat depth, average back fat depth, back fat weight, ham sub

Název v anglickém jazyce

Allelic variation in porcine resistin (RETN) gene is associated with fatness traits in a Wild Boar x Meishan reference family

Popis výsledku anglicky

Cloning and comparative sequencing of the porcine resistin (RETN) gene and 5? flanking region, located at 64 cM on SSC2, revealed 9 SNPs and 2 indels. A European Wild Boar x Meishan family encompassing 335 F2 animals measured for 46 traits including growth, fat deposition and muscle accretion was scored for a T2094C polymorphism by means of MvaI PCR-RFLP. Two haplotypes (AM157180 and AM157181) segregated in the family while the imprinted QTL in IGF2 was fixed. The founder boar was homozygote MvaI BB while Meishan F0 sows segregated alleles MvaI A and MvaI B. Previous QTL mapping by Lee et al. (2003) did not reveal any QTL for fat accretion in the MYOD - SW395 interval where RETN is located. Association analysis showed that the MvaI A allele of Meishanorigin accompanied by the 1472A allele encoding for 36Ala is associated with higher values for fat deposition traits (fat depth at 10th rib, back fat depth at 13th/14th rib, loin fat depth, average back fat depth, back fat weight, ham sub

Druh

D - Stať ve sborníku

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

<a href="/cs/project/GA523%2F04%2F0106" target="_blank" >GA523/04/0106: Molekulárně genetické studium variability ukládání tuku u prasat</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Proceedings of the 30th International Conference on Animal Genetics ISAG 2006

ISBN

85-85584-02-5

ISSN

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e-ISSN

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Počet stran výsledku

1

Strana od-do

72

Název nakladatele

ISAG

Místo vydání

Porto Seguro

Místo konání akce

Porto Seguro

Datum konání akce

20. 8. 2006

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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