Tooth-bone morphogenesis during postnatal stages of mouse first molar development

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F11%3A00360057" target="_blank" >RIV/67985904:_____/11:00360057 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62157124:16170/11:43870592 RIV/61989592:15310/11:33119841

Výsledek na webu

<a href="http://dx.doi.org/10.1111/j.1469-7580.2011.01367.x" target="_blank" >http://dx.doi.org/10.1111/j.1469-7580.2011.01367.x</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/j.1469-7580.2011.01367.x" target="_blank" >10.1111/j.1469-7580.2011.01367.x</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Tooth-bone morphogenesis during postnatal stages of mouse first molar development

Popis výsledku v původním jazyce

The first mouse molar (M1) is the most common model for odontogenesis, with research particularly focused on prenatal development. However, the functional dentition forms postnatally, when the histogenesis and morphogenesis of the tooth is completed, theroots form and the tooth physically anchors into the jaw. In this work, M1 was studied from birth to eruption, assessing morphogenesis, proliferation and apoptosis, and correlating these with remodeling of the surrounding bony tissue. The M1 completed crown formation between postnatal (P) days 0-2, and the development of the tooth root was initiated at P4. From P2 until P12, cell proliferation in the dental epithelium reduced and shifted downward to the apical region of the forming root. In contrast, proliferation was maintained or increased in the mesenchymal cells of the dental follicle. At later stages, before tooth eruption (P20), cell proliferation suddenly ceased.

Název v anglickém jazyce

Tooth-bone morphogenesis during postnatal stages of mouse first molar development

Popis výsledku anglicky

The first mouse molar (M1) is the most common model for odontogenesis, with research particularly focused on prenatal development. However, the functional dentition forms postnatally, when the histogenesis and morphogenesis of the tooth is completed, theroots form and the tooth physically anchors into the jaw. In this work, M1 was studied from birth to eruption, assessing morphogenesis, proliferation and apoptosis, and correlating these with remodeling of the surrounding bony tissue. The M1 completed crown formation between postnatal (P) days 0-2, and the development of the tooth root was initiated at P4. From P2 until P12, cell proliferation in the dental epithelium reduced and shifted downward to the apical region of the forming root. In contrast, proliferation was maintained or increased in the mesenchymal cells of the dental follicle. At later stages, before tooth eruption (P20), cell proliferation suddenly ceased.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EA - Morfologické obory a cytologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Anatomy

ISSN

0021-8782

e-ISSN

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Svazek periodika

218

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

18

Strana od-do

699-716

Kód UT WoS článku

000290176400012

EID výsledku v databázi Scopus

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