Coley's toxin and BCG vaccine in prevention and treatment of malignant melanoma in humans

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F17%3A00486690" target="_blank" >RIV/67985904:_____/17:00486690 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1097/MRM.0000000000000108" target="_blank" >http://dx.doi.org/10.1097/MRM.0000000000000108</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/MRM.0000000000000108" target="_blank" >10.1097/MRM.0000000000000108</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Coley's toxin and BCG vaccine in prevention and treatment of malignant melanoma in humans

Popis výsledku v původním jazyce

Malignant melanoma is the most severe form of skin cancers in humans. Incidence of this malignancy is still increasing worldwide. The highest incidence is mentioned in Australia (50-60/100,000 of cases). Success of malignant melanoma therapy depends on the stage of disease revelation. Localized cutaneous melanoma is generally well curable. The main problem is the treatment of advanced malignant melanoma with distant metastases. Therapy of this malignancy is based on surgical resection of lesion, chemotherapy, immunotherapy, biochemotherapy, and so on. The current results of malignant melanoma treatment are unfortunately often unsatisfactory. Improvement and enhancement of efficacy of contemporary immunotherapeutic methods should be in the forefront of interest. Renaissance of the old concepts of immunotherapy (Coley's toxin and Bacillus Calmette-Guerin vaccine administration) could be one way to reduce possible adverse effect of standard methods of malignant melanoma treatment.

Název v anglickém jazyce

Coley's toxin and BCG vaccine in prevention and treatment of malignant melanoma in humans

Popis výsledku anglicky

Malignant melanoma is the most severe form of skin cancers in humans. Incidence of this malignancy is still increasing worldwide. The highest incidence is mentioned in Australia (50-60/100,000 of cases). Success of malignant melanoma therapy depends on the stage of disease revelation. Localized cutaneous melanoma is generally well curable. The main problem is the treatment of advanced malignant melanoma with distant metastases. Therapy of this malignancy is based on surgical resection of lesion, chemotherapy, immunotherapy, biochemotherapy, and so on. The current results of malignant melanoma treatment are unfortunately often unsatisfactory. Improvement and enhancement of efficacy of contemporary immunotherapeutic methods should be in the forefront of interest. Renaissance of the old concepts of immunotherapy (Coley's toxin and Bacillus Calmette-Guerin vaccine administration) could be one way to reduce possible adverse effect of standard methods of malignant melanoma treatment.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30102 - Immunology

Projekt

<a href="/cs/project/LO1609" target="_blank" >LO1609: Modely závažných lidských onemocnění: Traumatické poškození míchy, Huntingtonova choroba, melanom a neplodnost</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Reviews in Medical Microbiology

ISSN

0954-139X

e-ISSN

—

Svazek periodika

28

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

124-128

Kód UT WoS článku

000404652600007

EID výsledku v databázi Scopus

2-s2.0-85021803377