Evolution of B Chromosomes: From Dispensable Parasitic Chromosomes to Essential Genomic Players

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F21%3A00551990" target="_blank" >RIV/67985904:_____/21:00551990 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11310/21:10438863

Výsledek na webu

<a href="https://www.frontiersin.org/articles/10.3389/fgene.2021.727570/full" target="_blank" >https://www.frontiersin.org/articles/10.3389/fgene.2021.727570/full</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fgene.2021.727570" target="_blank" >10.3389/fgene.2021.727570</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Evolution of B Chromosomes: From Dispensable Parasitic Chromosomes to Essential Genomic Players

Popis výsledku v původním jazyce

B chromosomes represent additional chromosomes found in many eukaryotic organisms. Their origin is not completely understood but recent genomic studies suggest that they mostly arise through rearrangements and duplications from standard chromosomes. They can occur in single or multiple copies in a cell and are usually present only in a subset of individuals in the population. Because B chromosomes frequently show unstable inheritance, their maintenance in a population is often associated with meiotic drive or other mechanisms that increase the probability of their transmission to the next generation. For all these reasons, B chromosomes have been commonly considered to be nonessential, selfish, parasitic elements. Although it was originally believed that B chromosomes had little or no effect on an organism's biology and fitness, a growing number of studies have shown that B chromosomes can play a significant role in processes such as sex determination, pathogenicity and resistance to pathogens. In some cases, B chromosomes became an essential part of the genome, turning into new sex chromosomes or germline-restricted chromosomes with important roles in the organism's fertility. Here, we review such cases of cellular domestication of B chromosomes and show that B chromosomes can be important genomic players with significant evolutionary impact.

Název v anglickém jazyce

Evolution of B Chromosomes: From Dispensable Parasitic Chromosomes to Essential Genomic Players

Popis výsledku anglicky

B chromosomes represent additional chromosomes found in many eukaryotic organisms. Their origin is not completely understood but recent genomic studies suggest that they mostly arise through rearrangements and duplications from standard chromosomes. They can occur in single or multiple copies in a cell and are usually present only in a subset of individuals in the population. Because B chromosomes frequently show unstable inheritance, their maintenance in a population is often associated with meiotic drive or other mechanisms that increase the probability of their transmission to the next generation. For all these reasons, B chromosomes have been commonly considered to be nonessential, selfish, parasitic elements. Although it was originally believed that B chromosomes had little or no effect on an organism's biology and fitness, a growing number of studies have shown that B chromosomes can play a significant role in processes such as sex determination, pathogenicity and resistance to pathogens. In some cases, B chromosomes became an essential part of the genome, turning into new sex chromosomes or germline-restricted chromosomes with important roles in the organism's fertility. Here, we review such cases of cellular domestication of B chromosomes and show that B chromosomes can be important genomic players with significant evolutionary impact.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

Projekt

<a href="/cs/project/GA20-23794S" target="_blank" >GA20-23794S: Chromozom specifický pro germinální linii pěvců: porozumění jeho vzniku, funkci a roli v evoluci</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Frontiers in genetics

ISSN

1664-8021

e-ISSN

1664-8021

Svazek periodika

12

Číslo periodika v rámci svazku

DEC 9

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

11

Strana od-do

727570

Kód UT WoS článku

000738341200001

EID výsledku v databázi Scopus

2-s2.0-85121715285