A pilot study: Exploring the influence of COVID-19 on cardiovascular physiology and retinal microcirculation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F23%3A00575032" target="_blank" >RIV/67985904:_____/23:00575032 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14310/23:00133041

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0026286223001140?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0026286223001140?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.mvr.2023.104588" target="_blank" >10.1016/j.mvr.2023.104588</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A pilot study: Exploring the influence of COVID-19 on cardiovascular physiology and retinal microcirculation

Popis výsledku v původním jazyce

Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the cardiovascular sys-tem. The current study investigated changes in heart rate (HR), blood pressure (BP), pulse wave velocity (PWV), and microcirculation in patients recovering from Coronavirus disease 2019 (COVID-19) infection.Methodology: Out of 43 initially contacted COVID-19 patients, 35 (30 males, 5 females, age: 60 & PLUSMN, 10 years, and body mass index (BMI): 31.8 & PLUSMN, 4.9) participated in this study. Participants were seen on two occasions after hospital discharge, the baseline measurements were collected, either on the day of hospital discharge if a negative PCR test was obtained, or on the 10th day after hospitalization if the PCR test was positive. The second measurements were done 60 days after hospitalization. The vascular measurements were performed using the VICORDER & REG, device and a retinal blood vessel image analysis. Results: A significant increase in systolic BP (SBP) (from 142 mmHg, SD: 15, to 150 mmHg, SD: 19, p = 0.041), reduction in HR (from 76 bpm, SD: 15, to 69 bpm, SD: 11, p = 0.001), and narrower central retinal vein equivalent (CRVE) (from 240.94 & mu,m, SD: 16.05, to 198.05 & m,m, SD: 17.36, p = 0.013) were found. Furthermore, the trends of increasing PWV (from 11 m/s, SD: 3, to 12 m/s, SD: 3, p = 0.095) and decreasing CRAE (from 138.87 & mu,m, SD: 12.19, to 136.77 & mu,m, SD: 13.19, p = 0.068) were recorded.Conclusion: The present study investigated cardiovascular changes following COVID-19 infection at two-time points after hospital discharge (baseline measurements and 60 days post-hospitalization). Significant changes were found in systolic blood pressure, heart rate, and microvasculature indicating that vascular adaptations may be ongoing even weeks after hospitalization from COVID-19 infection. Future studies could involve conducting additional interim assessments during the active infection and post-infection periods.

Název v anglickém jazyce

A pilot study: Exploring the influence of COVID-19 on cardiovascular physiology and retinal microcirculation

Popis výsledku anglicky

Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the cardiovascular sys-tem. The current study investigated changes in heart rate (HR), blood pressure (BP), pulse wave velocity (PWV), and microcirculation in patients recovering from Coronavirus disease 2019 (COVID-19) infection.Methodology: Out of 43 initially contacted COVID-19 patients, 35 (30 males, 5 females, age: 60 & PLUSMN, 10 years, and body mass index (BMI): 31.8 & PLUSMN, 4.9) participated in this study. Participants were seen on two occasions after hospital discharge, the baseline measurements were collected, either on the day of hospital discharge if a negative PCR test was obtained, or on the 10th day after hospitalization if the PCR test was positive. The second measurements were done 60 days after hospitalization. The vascular measurements were performed using the VICORDER & REG, device and a retinal blood vessel image analysis. Results: A significant increase in systolic BP (SBP) (from 142 mmHg, SD: 15, to 150 mmHg, SD: 19, p = 0.041), reduction in HR (from 76 bpm, SD: 15, to 69 bpm, SD: 11, p = 0.001), and narrower central retinal vein equivalent (CRVE) (from 240.94 & mu,m, SD: 16.05, to 198.05 & m,m, SD: 17.36, p = 0.013) were found. Furthermore, the trends of increasing PWV (from 11 m/s, SD: 3, to 12 m/s, SD: 3, p = 0.095) and decreasing CRAE (from 138.87 & mu,m, SD: 12.19, to 136.77 & mu,m, SD: 13.19, p = 0.068) were recorded.Conclusion: The present study investigated cardiovascular changes following COVID-19 infection at two-time points after hospital discharge (baseline measurements and 60 days post-hospitalization). Significant changes were found in systolic blood pressure, heart rate, and microvasculature indicating that vascular adaptations may be ongoing even weeks after hospitalization from COVID-19 infection. Future studies could involve conducting additional interim assessments during the active infection and post-infection periods.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30303 - Infectious Diseases

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Microvascular Research

ISSN

0026-2862

e-ISSN

1095-9319

Svazek periodika

150

Číslo periodika v rámci svazku

Nov 23

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

104588

Kód UT WoS článku

001049715900001

EID výsledku v databázi Scopus

2-s2.0-85165195733