A reappraisal of mitochondrial DNA introgression in the Mus musculus musculus/Mus musculus domesticus hybrid zone suggests ancient North-European associations between mice and humans

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F24%3A00599159" target="_blank" >RIV/67985904:_____/24:00599159 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68081766:_____/24:00599159 RIV/00216224:14310/24:00138547

Výsledek na webu

<a href="https://academic.oup.com/zoolinnean/article-abstract/202/1/zlae110/7758731?redirectedFrom=fulltext&login=true" target="_blank" >https://academic.oup.com/zoolinnean/article-abstract/202/1/zlae110/7758731?redirectedFrom=fulltext&login=true</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/zoolinnean/zlae110" target="_blank" >10.1093/zoolinnean/zlae110</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A reappraisal of mitochondrial DNA introgression in the Mus musculus musculus/Mus musculus domesticus hybrid zone suggests ancient North-European associations between mice and humans

Popis výsledku v původním jazyce

The house mouse is the best-studied mammal species after humans, yet our understanding of its evolutionary history remains incomplete. Here, we focused on the colonisation of Europe by two subspecies and formation of a hybrid zone between them. We carried out a large-scale study of similar to 7000 mice sampled across an area embracing an similar to 900 km long portion of the zone, supplemented with cytochrome b and D-loop sequencing of similar to 1200 individuals collected worldwide. We demonstrate that the course of the mtDNA contact front is intricate and highly discordant with the consensus front for autosomal and X-linked markers, suggesting that local snapshots of mtDNA introgression may be misleading when treated in isolation. While multiple unrelated M. m. domesticus haplotypes occur in the zone area, the diversity of M. m. musculus haplotypes is limited. Moreover, we uncovered a vast region of domesticus introgression into musculus territory in northern areas and showed this introgression is unlikely to be driven by positive selection. We consider two previously published hypotheses explaining this phenomenon and put forth an alternative scenario assuming associations between mice and humans in northern Europe during the Nordic Bronze Age and subsequent zone movement associated with the expansion of Balto-Slavic peoples.

Název v anglickém jazyce

A reappraisal of mitochondrial DNA introgression in the Mus musculus musculus/Mus musculus domesticus hybrid zone suggests ancient North-European associations between mice and humans

Popis výsledku anglicky

The house mouse is the best-studied mammal species after humans, yet our understanding of its evolutionary history remains incomplete. Here, we focused on the colonisation of Europe by two subspecies and formation of a hybrid zone between them. We carried out a large-scale study of similar to 7000 mice sampled across an area embracing an similar to 900 km long portion of the zone, supplemented with cytochrome b and D-loop sequencing of similar to 1200 individuals collected worldwide. We demonstrate that the course of the mtDNA contact front is intricate and highly discordant with the consensus front for autosomal and X-linked markers, suggesting that local snapshots of mtDNA introgression may be misleading when treated in isolation. While multiple unrelated M. m. domesticus haplotypes occur in the zone area, the diversity of M. m. musculus haplotypes is limited. Moreover, we uncovered a vast region of domesticus introgression into musculus territory in northern areas and showed this introgression is unlikely to be driven by positive selection. We consider two previously published hypotheses explaining this phenomenon and put forth an alternative scenario assuming associations between mice and humans in northern Europe during the Nordic Bronze Age and subsequent zone movement associated with the expansion of Balto-Slavic peoples.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10613 - Zoology

Projekt

<a href="/cs/project/GA16-23773S" target="_blank" >GA16-23773S: Fylogeografie, selekce a mutační rychlost na celogenomové úrovni: inference založená na sekvencích mtDNA myši domácí</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Zoological Journal of the Linnean Society

ISSN

0024-4082

e-ISSN

1096-3642

Svazek periodika

202

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

16

Strana od-do

zlae110

Kód UT WoS článku

001313848800001

EID výsledku v databázi Scopus

2-s2.0-85204348058