Comparison of non-synonymous/synonymous (dN/dS) ratios shows little evidence for a faster-Z effect in Furcifer chameleons after controlling for gene-specific evolutionary rates

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F25%3A00640312" target="_blank" >RIV/67985904:_____/25:00640312 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11310/25:10514248

Výsledek na webu

<a href="https://academic.oup.com/jhered/article-abstract/116/5/582/7906845?redirectedFrom=fulltext&login=true" target="_blank" >https://academic.oup.com/jhered/article-abstract/116/5/582/7906845?redirectedFrom=fulltext&login=true</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/jhered/esae070" target="_blank" >10.1093/jhered/esae070</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Comparison of non-synonymous/synonymous (dN/dS) ratios shows little evidence for a faster-Z effect in Furcifer chameleons after controlling for gene-specific evolutionary rates

Popis výsledku v původním jazyce

The faster-X/Z effect hypothesis states that genes linked to X/Z chromosomes should accumulate mutations faster than autosomal genes. Although faster evolution of X/Z-linked genes has been reported in several plant and animal lineages, conflicting results have been reported in others. We examined the faster-Z effect in chameleons of the genus Furcifer, a lineage with differentiated ZZ/ZW chromosomes for at least 20 million yr. We sequenced the genomes of four species of Furcifer chameleons in the Illumina platform and compared the substitution rates of synonymous and non-synonymous mutations and their ratios among autosomal, Z-specific, and pseudoautosomal protein-coding genes. The inclusion of two chameleon outgroups lacking the differentiated ZZ/ZW sex chromosomes allowed us to control for gene-specific evolutionary rates that might confound the testing of the faster-X/Z effect. Significant differences in evolutionary rates were found between autosomal, Z-specific, and pseudoautosomal genes of Furcifer chameleons. However, the inclusion of the outgroups with different sex chromosomes suggests that these genes had different evolutionary rates prior to their incorporation into the differentiated ZZ/ZW sex chromosomes of the Furcifer genus. The results highlight the need to control for differences in the evolutionary rates of individual genes when testing for the faster-X/Z effect.

Název v anglickém jazyce

Comparison of non-synonymous/synonymous (dN/dS) ratios shows little evidence for a faster-Z effect in Furcifer chameleons after controlling for gene-specific evolutionary rates

Popis výsledku anglicky

The faster-X/Z effect hypothesis states that genes linked to X/Z chromosomes should accumulate mutations faster than autosomal genes. Although faster evolution of X/Z-linked genes has been reported in several plant and animal lineages, conflicting results have been reported in others. We examined the faster-Z effect in chameleons of the genus Furcifer, a lineage with differentiated ZZ/ZW chromosomes for at least 20 million yr. We sequenced the genomes of four species of Furcifer chameleons in the Illumina platform and compared the substitution rates of synonymous and non-synonymous mutations and their ratios among autosomal, Z-specific, and pseudoautosomal protein-coding genes. The inclusion of two chameleon outgroups lacking the differentiated ZZ/ZW sex chromosomes allowed us to control for gene-specific evolutionary rates that might confound the testing of the faster-X/Z effect. Significant differences in evolutionary rates were found between autosomal, Z-specific, and pseudoautosomal genes of Furcifer chameleons. However, the inclusion of the outgroups with different sex chromosomes suggests that these genes had different evolutionary rates prior to their incorporation into the differentiated ZZ/ZW sex chromosomes of the Furcifer genus. The results highlight the need to control for differences in the evolutionary rates of individual genes when testing for the faster-X/Z effect.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

Projekt

<a href="/cs/project/GA23-07347S" target="_blank" >GA23-07347S: Co řídí diferenciaci pohlavních chromosomů? Výzva klasickým modelům</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Heredity

ISSN

0022-1503

e-ISSN

1465-7333

Svazek periodika

116

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

582-590

Kód UT WoS článku

001379159600001

EID výsledku v databázi Scopus

2-s2.0-105014636836