Izolace a endotoxinová aktivita lipopolysacharidů cyanobakteriálních kultur a komplexního vodního květu a srovnání s endotoxinovou aktivitou heterotrofních bakterií a řas

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985939%3A_____%2F08%3A00306706" target="_blank" >RIV/67985939:_____/08:00306706 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60077344:_____/08:00306706

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Isolation and endotoxin activities of lipopolysaccharides from cyanobacterial cultures and complex water blooms and comparison with the effects of heterotrophic bacteria and green alga

Popis výsledku v původním jazyce

Massive cyanobacterial water blooms are serious environmental problems worldwide. While some cyanobacterial toxins have been investigated extensively, other toxic components of cyanobacteria (lipopolysaccharides, LPS) are poorly understood. The present study characterized endotoxin activities of LPS isolated from cyanobacterial cultures, cyanobacterial water bloom samples, heterotrophic G- bacteria and green alga. Toxicity results derived with Limulus amebocyte lysate assay showed that endotoxin activities of LPS from both cyanobacteria and heterotrophic bacteria were comparable and within a similar range. The highest activities among the cyanobacterial samples were observed in the Aphanizomenon sp. dominated water bloom. The results also suggest generally higher endotoxin activities in complex natural samples than in laboratory cyanobacterial cultures. Further research should focus on detailed toxicological characterization of LPS in massive cyanobacterial water blooms.

Název v anglickém jazyce

Isolation and endotoxin activities of lipopolysaccharides from cyanobacterial cultures and complex water blooms and comparison with the effects of heterotrophic bacteria and green alga

Popis výsledku anglicky

Massive cyanobacterial water blooms are serious environmental problems worldwide. While some cyanobacterial toxins have been investigated extensively, other toxic components of cyanobacteria (lipopolysaccharides, LPS) are poorly understood. The present study characterized endotoxin activities of LPS isolated from cyanobacterial cultures, cyanobacterial water bloom samples, heterotrophic G- bacteria and green alga. Toxicity results derived with Limulus amebocyte lysate assay showed that endotoxin activities of LPS from both cyanobacteria and heterotrophic bacteria were comparable and within a similar range. The highest activities among the cyanobacterial samples were observed in the Aphanizomenon sp. dominated water bloom. The results also suggest generally higher endotoxin activities in complex natural samples than in laboratory cyanobacterial cultures. Further research should focus on detailed toxicological characterization of LPS in massive cyanobacterial water blooms.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EH - Ekologie – společenstva

OECD FORD obor

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Projekt

<a href="/cs/project/KJB6005411" target="_blank" >KJB6005411: Vodní květy sinic a cyanotoxiny v nádržích ČR - trendy a nové mechanismy toxicity</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2008

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Applied Toxicology

ISSN

0260-437X

e-ISSN

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Svazek periodika

28

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

72-77

Kód UT WoS článku

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EID výsledku v databázi Scopus

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