Neopicrorhiza scrophulariiflora (Pennell) Hong: A comprehensive review of its traditional uses, phytochemistry, pharmacology and safety

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985939%3A_____%2F20%3A00532384" target="_blank" >RIV/67985939:_____/20:00532384 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/86652079:_____/20:00517341 RIV/00216208:11310/20:10403151

Výsledek na webu

<a href="http://hdl.handle.net/11104/0310895" target="_blank" >http://hdl.handle.net/11104/0310895</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jep.2019.112250" target="_blank" >10.1016/j.jep.2019.112250</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Neopicrorhiza scrophulariiflora (Pennell) Hong: A comprehensive review of its traditional uses, phytochemistry, pharmacology and safety

Popis výsledku v původním jazyce

Ethnopharmacological relevance: Neopicrorhiza scrophulariiflora (Pennell) Hong is important medicinal plant that is native to the eastern Himalayas and Hengduan mountains in China. It is also distributed in Nepal, north east India, Bhutan and northern Myanmar. Plant parts are traditionally used against different kinds of diseases and various compounds present in different plant parts are also effective against many diseases. Thus, N. scrophulariiflora has a high potential to maintain human health. Aim of the review: Although N. scrophulariiflora is very important and widely studied plant species but there is no comprehensive up-to-date review of published and unpublished literature. So, in the present article we have compiled and critically commented on the botanical characteristics, traditional uses, plant growth and cultivation, micropropagation, conservation status, secondary metabolites, pharmacology and toxicity of the plant. Materials and methods: Extensive literature searches both electronic online databases (Google Scholar, Scopus, Springer Link, Web of Science, ScienceDirect, ResearchGate, PubMed, ChemSpider, USPTO, Google patents and Espacenet) and library visits in Nepal were carried out to collect the literature on information published prior to April 2019. Results: N. scrophulariiflora was traditionally used for 82 ailments/diseases. There are 124 major phytochemicals extracted from the plant. Several compounds are effective in bioactivity. Pharmacologically, the plant is proved to be anti-atherosclerotic, antidiabetic and anti-inflammatory in-vivo studies, and antimicrobial, antimalarial, antioxidative, hepatoprotective, immunomodulatory and nerve growth factor potentiating from in-vitro studies. Renal improvement activities were confirmed from both in-vivo and in-vitro studies. Toxicological tests and a single clinical trial in human beings have supported the notion that the plant is not poisonous but beneficial for curing wide ranges of diseases. Conclusion: N. scrophulariiflora is valuable medicinal plant that can serve as promising source of non-harmful and potential medicinal herbal remedies for human beings.

Název v anglickém jazyce

Neopicrorhiza scrophulariiflora (Pennell) Hong: A comprehensive review of its traditional uses, phytochemistry, pharmacology and safety

Popis výsledku anglicky

Ethnopharmacological relevance: Neopicrorhiza scrophulariiflora (Pennell) Hong is important medicinal plant that is native to the eastern Himalayas and Hengduan mountains in China. It is also distributed in Nepal, north east India, Bhutan and northern Myanmar. Plant parts are traditionally used against different kinds of diseases and various compounds present in different plant parts are also effective against many diseases. Thus, N. scrophulariiflora has a high potential to maintain human health. Aim of the review: Although N. scrophulariiflora is very important and widely studied plant species but there is no comprehensive up-to-date review of published and unpublished literature. So, in the present article we have compiled and critically commented on the botanical characteristics, traditional uses, plant growth and cultivation, micropropagation, conservation status, secondary metabolites, pharmacology and toxicity of the plant. Materials and methods: Extensive literature searches both electronic online databases (Google Scholar, Scopus, Springer Link, Web of Science, ScienceDirect, ResearchGate, PubMed, ChemSpider, USPTO, Google patents and Espacenet) and library visits in Nepal were carried out to collect the literature on information published prior to April 2019. Results: N. scrophulariiflora was traditionally used for 82 ailments/diseases. There are 124 major phytochemicals extracted from the plant. Several compounds are effective in bioactivity. Pharmacologically, the plant is proved to be anti-atherosclerotic, antidiabetic and anti-inflammatory in-vivo studies, and antimicrobial, antimalarial, antioxidative, hepatoprotective, immunomodulatory and nerve growth factor potentiating from in-vitro studies. Renal improvement activities were confirmed from both in-vivo and in-vitro studies. Toxicological tests and a single clinical trial in human beings have supported the notion that the plant is not poisonous but beneficial for curing wide ranges of diseases. Conclusion: N. scrophulariiflora is valuable medicinal plant that can serve as promising source of non-harmful and potential medicinal herbal remedies for human beings.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10611 - Plant sciences, botany

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Ethnopharmacology

ISSN

0378-8741

e-ISSN

—

Svazek periodika

247

Číslo periodika v rámci svazku

JAN 30

Stát vydavatele periodika

IE - Irsko

Počet stran výsledku

16

Strana od-do

1-16

Kód UT WoS článku

000497253400003

EID výsledku v databázi Scopus

2-s2.0-85072985088