Interspecies interactions can enhance Pseudomonas aeruginosa tolerance to surfaces functionalized with silver nanoparticles

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985939%3A_____%2F20%3A00533779" target="_blank" >RIV/67985939:_____/20:00533779 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14310/20:00116506 RIV/61989592:15310/20:73603990

Výsledek na webu

<a href="https://doi.org/10.1016/j.colsurfb.2020.111027" target="_blank" >https://doi.org/10.1016/j.colsurfb.2020.111027</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.colsurfb.2020.111027" target="_blank" >10.1016/j.colsurfb.2020.111027</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Interspecies interactions can enhance Pseudomonas aeruginosa tolerance to surfaces functionalized with silver nanoparticles

Popis výsledku v původním jazyce

Development of anti-fouling surfaces is a major challenge in materials research. Microorganisms growing as biofilms have enhanced tolerance to antimicrobial strategies including antibiotics and antiseptics complicating the design of anti-fouling surfaces. Silver nanoparticles (AgNPs) are a promising antimicrobial technology with broad spectrum efficacy with a reduced likelihood of microorganisms developing resistance to the technology. This study tested the efficacy of new immobilized AgNP-modified surface technology against three common opportunistic pathogens grown either as monocultures or as cocultures. The presented study fills a gap in the literature by quantifying the efficacy of immobilized AgNP particles against multispecies biofilms. Polyethylene (PE) surfaces functionalized with the AgNPs were highly effective against Pseudomonas aeruginosa biofilms reducing viable cell counts by 99.8 % as compared to controls. However, the efficacy of the AgNP-modified PE surface was compromised when P. aeruginosa was cocultured with Candida albicans. Interspecies interactions can strongly influence the efficacy of anti-fouling AgNP coatings highlighting the need to test surfaces not only against biofilm phenotypes but under conditions representative of applications including the presence of multispecies consortia.

Název v anglickém jazyce

Interspecies interactions can enhance Pseudomonas aeruginosa tolerance to surfaces functionalized with silver nanoparticles

Popis výsledku anglicky

Development of anti-fouling surfaces is a major challenge in materials research. Microorganisms growing as biofilms have enhanced tolerance to antimicrobial strategies including antibiotics and antiseptics complicating the design of anti-fouling surfaces. Silver nanoparticles (AgNPs) are a promising antimicrobial technology with broad spectrum efficacy with a reduced likelihood of microorganisms developing resistance to the technology. This study tested the efficacy of new immobilized AgNP-modified surface technology against three common opportunistic pathogens grown either as monocultures or as cocultures. The presented study fills a gap in the literature by quantifying the efficacy of immobilized AgNP particles against multispecies biofilms. Polyethylene (PE) surfaces functionalized with the AgNPs were highly effective against Pseudomonas aeruginosa biofilms reducing viable cell counts by 99.8 % as compared to controls. However, the efficacy of the AgNP-modified PE surface was compromised when P. aeruginosa was cocultured with Candida albicans. Interspecies interactions can strongly influence the efficacy of anti-fouling AgNP coatings highlighting the need to test surfaces not only against biofilm phenotypes but under conditions representative of applications including the presence of multispecies consortia.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

21002 - Nano-processes (applications on nano-scale); (biomaterials to be 2.9)

Projekt

<a href="/cs/project/EF17_048%2F0007323" target="_blank" >EF17_048/0007323: Rozvoj předaplikačního výzkumu v oblasti nano- a biotechnologií</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Colloids and Surfaces B-Biointerfaces

ISSN

0927-7765

e-ISSN

—

Svazek periodika

192

Číslo periodika v rámci svazku

AUG

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

1-8

Kód UT WoS článku

000542568000012

EID výsledku v databázi Scopus

2-s2.0-85084182804