Chiral separability of boron cluster species studied by screening approaches utilizing polysaccharide-based chiral stationary phases
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F14%3A00428338" target="_blank" >RIV/68081707:_____/14:00428338 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1002/bmc.3091" target="_blank" >http://dx.doi.org/10.1002/bmc.3091</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/bmc.3091" target="_blank" >10.1002/bmc.3091</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Chiral separability of boron cluster species studied by screening approaches utilizing polysaccharide-based chiral stationary phases
Popis výsledku v původním jazyce
In this study, the screening steps of chiral separation strategies with polysaccharide-based chiral stationary phases were applied on boron cluster compounds in normal-phase liquid chromatography (NPLC) and polar organic solvents chromatography (POSC). Since the screening steps were initially developed to analyze organic compounds, their applicability for boron clusters was investigated. Overall, the screening steps in NPLC were applicable for the separation of zwitterions, while for anions mostly no elution was observed. A hypothesis for the latter behavior is precipitation of anions in the nonpolar mobile phases. Ten out of 11 compounds could be partially or baseline separated on the NPLC screening systems. In POSC, all zwitterions were separated onat least one of the screening systems, with an overall lower retention as in NPLC. Anions were detected but not separated in the majority of the experiments. Also their retention on the chiral stationary phases was very limited.
Název v anglickém jazyce
Chiral separability of boron cluster species studied by screening approaches utilizing polysaccharide-based chiral stationary phases
Popis výsledku anglicky
In this study, the screening steps of chiral separation strategies with polysaccharide-based chiral stationary phases were applied on boron cluster compounds in normal-phase liquid chromatography (NPLC) and polar organic solvents chromatography (POSC). Since the screening steps were initially developed to analyze organic compounds, their applicability for boron clusters was investigated. Overall, the screening steps in NPLC were applicable for the separation of zwitterions, while for anions mostly no elution was observed. A hypothesis for the latter behavior is precipitation of anions in the nonpolar mobile phases. Ten out of 11 compounds could be partially or baseline separated on the NPLC screening systems. In POSC, all zwitterions were separated onat least one of the screening systems, with an overall lower retention as in NPLC. Anions were detected but not separated in the majority of the experiments. Also their retention on the chiral stationary phases was very limited.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
BO - Biofyzika
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2014
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Biomedical Chromatography
ISSN
0269-3879
e-ISSN
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Svazek periodika
28
Číslo periodika v rámci svazku
5
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
14
Strana od-do
694-707
Kód UT WoS článku
000334197400016
EID výsledku v databázi Scopus
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